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UnknownMulti-Institutional Phase II Study of High-Dose Hypofractionated Proton Beam Therapy in Patients With Localized, Unresectable Hepatocellular Carcinoma and Intrahepatic Cholangiocarcinoma.
Not available
S-EPMC4872014 | biostudies-literature
TranscriptomicsThe CrebA/Creb3-like transcription factors are major and direct regulators of secretory capacity
Abstract: Secretion occurs in all cells, with relatively low levels in most cells and extremely high levels in specialized secretory cells, such as those of the pancreas, salivary and mammary glands. Here, we report that the CrebA/Creb3-like family of bZip transcription factors functions to upregul...
ORGANISM(S): Homo sapiens 
2010-10-18 | E-GEOD-23349 | biostudies-arrayexpress
UnknownSARS-CoV-2 mRNA vaccination elicits a robust and persistent T follicular helper cell response in humans.
Not available
S-EPMC8695127 | biostudies-literature
TranscriptomicsExpression profiles from a variety of resting and activated human immune cells
Immune cell-specific expression is one indication of the importance of a gene's role in the immune response. In order to identify such patterns, we set out to broadly profile gene expression in a variety of immune cells. We isolated twelve different types of human leukocytes from peripheral blood an...
ORGANISM(S): Homo sapiens 
2010-07-13 | E-GEOD-22886 | biostudies-arrayexpress
UnknownThe Ethylene Oxide Product Test of Sterility: Limitations and Interpretation of Results.
Not available
S-EPMC8655700 | biostudies-literature
ProteomicsEffect of LPS and the glucocorticoid dexamethasone on the mouse Bone Marrow Derived Macrophage Proteome
The concentrations and copy number of proteins in the mouse Bone Marrow Derived proteome was determined for control, 10 ng/mL LPS stimulation, and LPS stimulation plus the addition of 100 nM dexamethasone, after an incubation for 24 hours and with four biological replicates for each condition. Over ...
ORGANISM(S): Mus musculus (Mouse) 
2024-01-26 | PXD041375 | Pride
Innate immunity Glucocorticoid Macrophage Dexamethasone Mouse Type i interferon 
GenomicsBase-pair level resolution of the Nasonia vitripennis methylome
The parasitoid wasp Nasonia vitripennis is an emerging genetic model for functional analysis of DNA methylation. Here, we characterize genome-wide methylation at a base-pair resolution, and compare these results to gene expression across five developmental stages and to methylation patterns reported...
ORGANISM(S): Nasonia vitripennis 
2013-08-27 | E-GEOD-43423 | biostudies-arrayexpress
UnknownThe CARD8 inflammasome dictates HIV/SIV pathogenesis and disease progression.
Not available
S-EPMC10919936 | biostudies-literature
GenomicsGene expression and epigenetic sexual dimorphism in two jewel wasp species Nasonia vitripennis and Nasonia giraulti [Bisulfite-Seq]
The extraordinary range in the degree of sexual dimorphism (SD) among animal species is widely perceived to be caused in part by differences in patterns of sexual selection, but sex-specific adaptations and sex chromosome differences also play a role. Studies in insects have discovered a substantial...
ORGANISM(S): Nasonia giraulti 
2015-06-08 | E-GEOD-61158 | biostudies-arrayexpress
TranscriptomicsRNA-seq to investigate differentially expressed genes in KPC mouse PDAC treated with CSF-1R small molecule inhibitor AZD7507 and/or the CXCR2 small molecule inhibitor AZD5069
Recently, we defined four subtypes of pancreatic cancer that are associated with distinct histopathological characteristics and differential survival, namely, Squamous, Pancreatic Progenitor, Immunogenic, and ADEX (Bailey et al 2016, Nature). We also found that loss of CXCR2 was associated with a sw...
ORGANISM(S): Mus musculus 
2018-05-01 | E-MTAB-6620 | biostudies-arrayexpress
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