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At present, substantial efforts are focused on the development of in vitro assays coupled with M-bM-^@M-^]omicsM-bM-^@M-^] technologies for the identification of carcinogenic substances as an alternative to the classical 2-year rodent carcinogenicity bioassay. A prerequisite for the eventual regulat...
ORGANISM(S): Rattus norvegicus 
Abstract: Clonidine has been used in clinical medicine, e.g. to treat high blood pressure, and its use has been linked to impairments of male fertility, but the underlying reasons are not known. Clonidine is an agonist at the α2A-adrenoceptor (ADRA2A) which is expressed by cells of the testis, hence...
ORGANISM(S): Homo sapiens (Human) 
2024-10-17 | PXD052220 | Pride
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