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Arthropods include chelicerates, crustaceans, and insects that all have open circulation systems and thus require different properties of their coagulation system than vertebrates. Although the clotting reaction in the chelicerate horseshoe crab has been described in details, the overall protein com...
ORGANISM(S): Acanthoscurria geniculata 
2017-01-11 | PXD002500 | Pride
The presence and amount of the proteins within a plasma clot may influence clot properties, like susceptibility to fibrinolysis, however, the plasma clot proteome has not yet been extensively described. The aim of the study was to investigate the protein composition of clots prepared ex vivo from pl...
ORGANISM(S): Homo sapiens (Human) 
2016-12-08 | PXD001109 | Pride
Antiphospholipid syndrome (APS) is associated with arterial and venous thrombosis. The unfavorable fibrin clot phenotype, including formation of dense and poorly lysable clots, has been reported both in thrombotic APS and venous thromboembolism (VTE). The presence and amount of different proteins wi...
ORGANISM(S): Homo sapiens (Human) 
2019-08-20 | PXD008434 | Pride
Specialized regulatory T cells control venous blood clot resolution through SPARC
The cells and mechanisms involved in blood clot resorption are only partially known. Regulatory T cells (Treg) accumulate in venous blood clots and regulate thrombolysis by controlling the recruitment, differentiation and matrix metalloproteinase (MMP) activity of monocytes. The clot Treg population...
ORGANISM(S): Mus musculus 
2023-06-01 | GSE155444 | GEO
Spatial Transcriptomic Analysis of a Human Bone Marrow Clot Biopsy Using Xenium 5K
A normal human bone marrow clot biopsy was analyzed using the Xenium 5K panel and annotated with BinarySPA.
ORGANISM(S): Homo sapiens 
2026-04-10 | GSE322974 | GEO
Secondary injury causes death and dependence after spontaneous intracerebral haemorrhage (ICH). We found that myelomononuclear Nrf2 is active and protective after ICH in mice. To investigate the roles of myelomononuclear Nrf2 in modulating cell autonomous and non-cell autonomous responses to the oxi...
ORGANISM(S): mixed sample 
This project involved analysis of healthy control and trauma patient clot proteomes.
ORGANISM(S): Homo sapiens (Human) 
2025-08-28 | PXD062639 | Pride
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