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In this project we establish the unit cell of fibrin polymer network by using of XL-MS methods and modelling approaches. With shotgun proteomics approach we estimate the ratio of proteins in the purified Fibrin Clots and ratio of Albumin inter- and intralinks
ORGANISM(S): Homo sapiens (Human) 
2020-01-09 | PXD011680 | Pride
Collagen- and fibrin-based gels are extensively used to study cell behaviour. However, 2D-3D, collagen-fibrin, and in vivo-in vitro comparisons of gene expression, cell shape and mechanotransduction have not been reported. Here we compared chick tendon fibroblasts (CTFs) at three stages of embryonic...
ORGANISM(S): Gallus gallus 
Here is an ode model for in vitro fibrin matrix polymerization reproducing interactions among fibrinogen, fibrin and other proteins involved in the homeostatic phase of wound healing.
2024-09-02 | BIOMD0000001054 | BioModels
Angiogenesis in cultures of rat aorta begins with neovessels sprouting from the aortic explant within the first three days of culture. We used microarrys to examine the effects of TNF-alpha on gene expression in both fibrin and collagen gels during the first 48 hours or culture. Rat aortic rings wer...
ORGANISM(S): Rattus norvegicus 
Mathematical model of the blood coagulation cascade. Extended Hockin model with contributions from Kim2007, Naski1991, Schneider2004, Horrevoets1996, Brummel-Ziedins2012, Mitrophanov2012, Danforth2009 and Hekman1988. Model incorporates more fibrin associated species such as fibrin I and II monomers ...
2018-06-26 | MODEL1806260001 | BioModels
Fibrin drives thromboinflammation and neuropathology in COVID-19 [NK_Fibrin_in_vitro]
Fibrin drives thromboinflammation and neuropathology in COVID-19 [Lung]
Our recent work showed COVID BALF from vaccinated individuals contained significantly lower concentration of fibrinogen and prothrombin, suggesting a potential benefit of vaccination being lower risk of fibrin clotting and acute lung injury. As our previous mass spec-based proteomic ID approach show...
ORGANISM(S): Homo sapiens (Human) 
2025-10-06 | PXD066557 | Pride
Expression data from fibrin-stimulated macrophages treated with 5B8 antibody or IgG2b control
Fibrin and GelMA hydrogel MEW-based human engineered cardiac tissue
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