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ProteomicsIdentification of N-linked glycosylated peptides in the open ocean diatom Thalassiosira oceanica
N-linked glycosylation is a posttranslational modification affecting protein folding and protein function. The N-linked glycosylation pathway in algae is poorly characterized, and further knowledge is needed to understand the cell biology of algae and the evolution of N-linked glycosylation. This st...
ORGANISM(S): Thalassiosira oceanica 
2021-09-09 | PXD021782 | Pride
Diatom Solid-phase extraction of n-linked glycosylated peptides N-linked glycosylation 
TranscriptomicsMOTS-c: A Novel Peptide Encoded by a Short Mitochondrial Open Reading Frame Regulates Metabolic Homeostasis
Mitochondria are known to be functional organelles, but their role as a signaling unit is increasingly being appreciated. The recent identification of a short open reading frame (sORF) in the mitochondrial DNA (mtDNA) that encodes a signaling peptide, humanin, suggests the possible existence of addi...
ORGANISM(S): Homo sapiens 
2015-03-07 | E-GEOD-65068 | biostudies-arrayexpress
MetabolomicsNQO1 protects obese mice through improvements in glucose and lipid metabolism.
Chronic nutrient excess leads to metabolic disorders and insulin resistance. Activation of stress-responsive pathways via Nrf2 activation contributes to energy metabolism regulation. Here, inducible activation of Nrf2 in mice and transgenesis of the Nrf2 target, NQO1, conferred protection from diet-...
2024-05-23 | MTBLS2085 | MetaboLights
UnknownA poor and delayed anti-SARS-CoV2 IgG response is associated to severe COVID-19 in children.
Not available
S-EPMC8502533 | biostudies-literature
ProteomicsImmunological Proteome Resource (ImmPRes): Part two
Second dataset release from the Immunological Proteome Resource (ImmPRes). This dataset contains both lymphoid and myeloid populations. The whole list is as follows: Bone marrow derived eosinophils, bone marrow derived mast cells, bone marrow derived macrophages, NK cells, TH2 cells, TH17 cells, Cyt...
ORGANISM(S): Mus musculus (Mouse) 
2020-07-02 | PXD020091 | Pride
Immpres  t cells  macrophages  mast cells  nk cells  tmt 
UnknownImpact and effectiveness of RSV maternal immunization on infant hospitalizations in Buenos Aires: a hospital-based, multicentre, retrospective surveillance cohort study.
Not available
S-EPMC12670925 | biostudies-literature
TranscriptomicsGrowth Hormone Receptor and IGF-I Deficiency is Associated with Resistance to DNA Damage and Very Low Cancer and Diabetes Incidence in Humans
Growth Hormone Receptor Deficiency (GHRD) in mice causes life span extension and a major increase in the portion of animals that die without detectable pathologies including cancer and insulin resistance. During a 22-year monitoring of a cohort of 0-88 year old Ecuadorian GHRD subjects with severe I...
ORGANISM(S): Homo sapiens 
2010-12-25 | E-GEOD-21980 | biostudies-arrayexpress
UnknownGenetic Testing to Inform Epilepsy Treatment Management From an International Study of Clinical Practice.
Not available
S-EPMC9623482 | biostudies-literature
UnknownIdentifying associations between diabetes and acute respiratory distress syndrome in patients with acute hypoxemic respiratory failure: an analysis of the LUNG SAFE database.
Not available
S-EPMC6203969 | biostudies-literature
UnknownPharmacokinetics of hydroxychloroquine in paediatric lupus: data from a novel, direct-to-family clinical trial.
Not available
S-EPMC9639143 | biostudies-literature
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