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GenomicsHigh-resolution transcriptome and genome-wide dynamics of RNA polymerase and NusA in Mycobacterium tuberculosis (ChIP-seq)
To construct a regulatory map of the genome of the human pathogen, Mycobacterium tuberculosis, we applied two complementary high-resolution approaches, strand-specific RNA-seq and ChIP-seq, to survey the global transcriptome and monitor genome-wide dynamics of RNA polymerase (RNAP) and NusA. ChIP-s...
ORGANISM(S): Mycobacterium tuberculosis 
2012-12-01 | E-GEOD-40845 | biostudies-arrayexpress
TranscriptomicsHigh-resolution transcriptome and genome-wide dynamics of RNA polymerase and NusA in Mycobacterium tuberculosis (RNA-seq)
To construct a regulatory map of the genome of the human pathogen, Mycobacterium tuberculosis, we applied two complementary high-resolution approaches, strand-specific RNA-seq and ChIP-seq, to survey the global transcriptome and monitor genome-wide dynamics of RNA polymerase (RNAP) and NusA. ChIP-s...
ORGANISM(S): Mycobacterium tuberculosis 
2012-12-01 | E-GEOD-40846 | biostudies-arrayexpress
UnknownLethal neonatal respiratory failure due to biallelic variants in BBS1 and monoallelic variant in TTC21B.
Not available
S-EPMC9744956 | biostudies-literature
ProteomicsespL deletion mutant of Mycobacterium tuberculosis
The ESX-1, type VII, secretion system represents the major virulence determinant of Mycobacterium tuberculosis, one of the most successful intracellular pathogens. Here, by combining genetic and high-throughput approaches, we show that EspL, a protein of 115 amino acids, is essential for mediating E...
ORGANISM(S): Mycobacterium tuberculosis H37Rv 
2018-12-10 | PXD010929 | Pride
Mycobacterium Virulence Tuberculosis Espl 
UnknownPresence, function, and regulation of IL-17F-expressing human CD4+ T cells.
Not available
S-EPMC7187427 | biostudies-literature
ProteomicsMass-spectrometry-based analysis of the secretome of M. tuberculosis mutants
The ESX-1, type VII, secretion system represents the major virulence determinant of Mycobacterium tuberculosis, one of the most successful intracellular pathogens. Here we study the proteme of various ESX-1 knock-out mutants.
ORGANISM(S): Mycobacterium tuberculosis H37Rv 
2018-12-10 | PXD011466 | Pride
Esx-1 Mycobacterium tuberculosis 
ProteomicsProteomic and phosphoproteomic profiling of SFTPCI73T expressing patient-specific pluripotent stem cell-derived alveolar epithelial type 2 cells and their gene-edited corrected counterparts.
We performed proteomic and phosphoproteomic profiling of cells derived from human induced pluripotent stem cells (iPSCs) using our previously described distal lung directed differentiation protocol to generate alveolar epithelial type 2 cells (iAEC2s). We used the SPC2 human iPSC line and specifical...
ORGANISM(S): Homo sapiens (Human) 
2021-10-07 | PXD022334 | Pride
Autophagy Proteomics Pluripotent stem cells Pulmonary fibrosis Alveolar epithelial type 2 cells 
UnknownInhibition of p300 impairs Foxp3⁺ T regulatory cell function and promotes antitumor immunity.
Not available
S-EPMC3793393 | biostudies-literature
UnknownMorphine alters the circulating proteolytic profile in mice: functional consequences on cellular migration and invasion.
Not available
S-EPMC5690391 | biostudies-literature
UnknownResponses to Quadrivalent Influenza Vaccine Reveal Distinct Circulating CD4+CXCR5+ T Cell Subsets in Men Living with HIV.
Not available
S-EPMC6821795 | biostudies-literature
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