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Ineffective endometrial matrix remodeling, a key factor in infertility, impedes embryo implantation in the uterine wall. Our study reveals the cellular and molecular impact of human collagenase-1 administration in mouse uteri, demonstrating enhanced embryo implantation rates. Collagenase-1 promotes ...
ORGANISM(S): Mus musculus (Mouse) 
2024-08-13 | PXD054389 | Pride
Objective Human primary articular chondrocytes (hPACs) are routinely isolated from articular cartilage and for pre-clinical OA research. Collagenase digest of tissue is an essential step, yet the impact of enzymatic incubation on the phenotype of hPACs is unclear. We aim to delineate this through p...
ORGANISM(S): Homo sapiens (Human) 
2025-10-20 | PXD064948 | Pride
Anomalous posterior vitreous detachment (aPVD) is involved in the pathogenesis of many vitreoretinal disorders. This condition is currently managed by vitrectomy, a routine but invasive surgery which is especially challenging in patients with firm vitreoretinal adhesions. Since 1998, pharmacological...
ORGANISM(S): Hathewaya Histolytica 
2026-02-10 | PXD060529 | panorama
We previously identified endothelial cell-selective adhesion molecule (ESAM) as a novel functional marker of hematopoietic stem cells (HSCs) in mice. To examine ESAM expression in human, we analyzed diverse HSC sources using flow cytometry. From mononuclear cells of collagenase-treated human hip bon...
ORGANISM(S): Homo sapiens 
Induced proteolysis of rat heart extracts with recombinant MMP-2 followed by subtiligase-N-terminomics
ORGANISM(S): Rattus (ncbitaxon:10114) 
2023-11-01 | MSV000093229 | MassIVE
RNA-seq of human mesenchymal stem cells cultured on collagenase material against tissue culture plastic controls
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