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ProteomicsIdentification of proteins that interacted with ESCO2
The Flag–ESCO2 plasmids were transfected into HEK293T cells, Flag–ESCO2 complexes were co-immunoprecipitated using an anti-Flag antibody. The Flag–ESCO2 complexes was separated using SDS PAGE, and then was identified by combining silver staining and mass spectrometry.
ORGANISM(S): Homo sapiens (Human) 
2021-09-10 | PXD023527 | Pride
Lc-ms Hek293t cells Esco2 Combining silver staining 
UnknownAntimicrobial potential and osteoblastic cell growth on electrochemically modified titanium surfaces with nanotubes and selenium or silver incorporation.
Not available
S-EPMC9117198 | biostudies-literature
UnknownSilver Nanoparticles Combined With Naphthoquinones as an Effective Synergistic Strategy Against Staphylococcus aureus.
Not available
S-EPMC6094968 | biostudies-literature
UnknownExploring the anticancer potential of green silver Nanoparticles-Paclitaxel nanocarrier on MCF-7 breast Cancer cells: an in vitro approach.
Not available
S-EPMC12181376 | biostudies-literature
TranscriptomicsIntegrated molecular pathway analysis informs a synergistic combination therapy targeting PTEN/PI3K and EGFR pathways for basal-like breast cancer.
Abstract BACKGROUND: The basal-like breast cancer (BLBC) subtype is characterized by positive staining for basal mammary epithelial cytokeratin markers, lack of hormone receptor and HER2 expression, and poor prognosis with currently no approved molecularly-targeted therapies. The oncogenic signaling...
ORGANISM(S): Homo sapiens 
2016-08-21 | E-GEOD-74667 | biostudies-arrayexpress
TranscriptomicsGENOME-WIDE CpG ISLAND METHYLATION ANALYSIS IN NON-SMALL CELL LUNG CANCER PATIENTS [Affymetrix expression data]
Epigenetic changes largely contribute to the regulation of gene expression in cancer cells. DNA methylation is part of the epigenetic gene regulation complex which is relevant for the pathogenesis of cancer. We performed a genome-wide search for methylated CpG islands in tumors and corresponding non...
ORGANISM(S): Homo sapiens 
2012-11-26 | E-GEOD-32496 | biostudies-arrayexpress
ProteomicsHULC interactome MS analysis
we report a high throughput strategy to screen for lncRNA interacting proteins in vivo by combining tobramycin affinity purification and mass spectrometric analysis (TOBAP-MS). This method was applied to establish the interactome network for the lncRNA highly-upregulated in liver cancer (HULC).
ORGANISM(S): Homo sapiens (Human) 
2020-07-02 | PXD012927 | Pride
Hulc Silac Gel-based proteomics 
ProteomicsIdentification of proteins that interacted with DPYSL2
Dihydropyrimidinase like 2 promotes bladder cancer progression via pyruvate kinase M2-induced aerobic glycolysis and epithelial–mesenchymal transition. DPYSL2 promotes bladder cancer progression via PKM2.
ORGANISM(S): Homo sapiens (Human) 
2021-09-09 | PXD023279 | Pride
Human Ls-msms Dpysl2 
TranscriptomicsSequential combination of decitabine and idarubicin synergistically enhances anti-leukemia effect by demethylating Wnt pathway inhibitor promoters and downregulating Wnt pathway nuclear target
Purpose: We aimed to investigate the effect of several anti-leukemia drugs in combination with decitabine (DAC) on the proliferation of myeloid leukemia cells in vitro and in vivo, to select the most efficient combination group and explore associated mechanisms of these combination therapies. Expe...
ORGANISM(S): Homo sapiens 
2014-02-13 | E-GEOD-54918 | biostudies-arrayexpress
TranscriptomicsCarfilzomib Suppresses SENP1 to Trigger Cardiotoxicity by DDX17 Destabilization
Carfilzomib has a good effect in treating multiple myeloma, but more and more clinical studies have shown that the drug can cause cardiac toxicity during use, but the mechanism of action is unclear. This study aimed to comprehensively elucidate the mechanism of CFZ-induced cardiomyopathy by construc...
ORGANISM(S): Rattus norvegicus 
2024-08-10 | GSE273971 | GEO
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