Sort   by:  
 Page size 
ProteomicsIdentification of proteins that interacted with ESCO2
The Flag–ESCO2 plasmids were transfected into HEK293T cells, Flag–ESCO2 complexes were co-immunoprecipitated using an anti-Flag antibody. The Flag–ESCO2 complexes was separated using SDS PAGE, and then was identified by combining silver staining and mass spectrometry.
ORGANISM(S): Homo sapiens (Human) 
2021-09-10 | PXD023527 | Pride
Lc-ms Hek293t cells Esco2 Combining silver staining 
Proteomicshuman ESCO2-interacting proteins in response to DNA damage
We used IP-MS to detected the proteins that interact with ESCO2 in response to DNA damage.
ORGANISM(S): Homo sapiens (Human) 
2023-10-24 | PXD039072 | Pride
Huamn Esco2 Dna damage 
TranscriptomicsExpression data from zebrafish depleted of Esco2
Our study in zebrafish is the first to use an animal model to understand the biology of the developmental disorder Roberts Syndrome (RBS). RBS is caused by mutations in the ESCO2 gene. We have used morpholinos (MO) to knock down esco2 in zebrafish to better understand the pathology of this rare huma...
ORGANISM(S): Danio rerio 
2011-03-01 | E-GEOD-27569 | biostudies-arrayexpress
TranscriptomicsImproved transcription and translation with L-leucine stimulation of mTORC1
Roberts syndrome (RBS) is a human developmental disorder caused by mutations in the cohesin acetyltransferase ESCO2. We previously reported that mTORC1 was inhibited and overall translation was reduced in RBS cells. Treatment of RBS cells with L-leucine partially rescued mTOR function and protein sy...
ORGANISM(S): Homo sapiens 
2016-01-15 | E-GEOD-64962 | biostudies-arrayexpress
TranscriptomicsExpression data from zebrafish depleted of Esco2
Our study in zebrafish is the first to use an animal model to understand the biology of the developmental disorder Roberts Syndrome (RBS). RBS is caused by mutations in the ESCO2 gene. We have used morpholinos (MO) to knock down esco2 in zebrafish to better understand the pathology of this rare huma...
ORGANISM(S): Danio rerio 
2011-03-01 | GSE27569 | GEO
GenomicsEsco2 restrains pathological endothelial-to-mesenchymal transition through hidden isoform regulation in a Roberts syndrome model
Esco2 restrains pathological endothelial-to-mesenchymal transition through hidden isoform regulation in a Roberts syndrome model
PRJNA1515232 | ENA
UnknownThe cohesin modifier ESCO2 is stable during DNA replication.
Not available
S-EPMC9884251 | biostudies-literature
UnknownESCO2 promotes hypopharyngeal carcinoma progression in a STAT1-dependent manner.
Not available
S-EPMC10647066 | biostudies-literature
UnknownESCO2 promotes lung adenocarcinoma progression by regulating hnRNPA1 acetylation.
Not available
S-EPMC7876794 | biostudies-literature
GenomicsEsco2 restrains pathological endothelial-to-mesenchymal transition through hidden isoform regulation in a Roberts syndrome model
ESCO2 encodes a cohesin acetyltransferase required for embryonic development, but how ESCO2 deficiency disrupts endothelial cell state and vascular development remains incompletely understood. This study used conditional Esco2 deletion in embryonic yolk sac endothelium to investigate gene-expression...
ORGANISM(S): Mus musculus 
2026-09-14 | GSE344313 | GEO
Sort   by:  
 Page size