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ProteomicsSpecific mixing facilitates the comparative quantification of phosphorylation sites with significant dysregulations
It is still a big challenge to accurately quantify the proteins or proteins PTM sites with extreme relative abundances in comparative protein samples, such as the significantly dysregulated ones. Herein, a novel quantification strategy, Mixing at Specific Ratio (MaSR) before isotope labeling, had be...
ORGANISM(S): Candida albicans (Yeast) Homo sapiens (Human) Escherichia coli 
2016-12-06 | PXD005181 | Pride
Lc-msms Mixing at specific ratio Comparative phosphoproteome quantification Stable isotope labeling Extreme relative abundance 
ProteomicsComparative proteomics and phosphoproteomics analyses of glucocorticoid responses in breast cancer cell lines
Breast cancer is often treated with glucocorticoids together with chemotherapy to relieve its side effects. However, it has been reported that glucocorticoids promote metastasis of breast cancer. In this study, we conducted quantitative mass-spectrometry to acquire proteome and phosphoproteome to un...
ORGANISM(S): Homo sapiens (Human) 
2026-01-26 | PXD070780 | Pride
Phosphoproteome Glucocorticoid Breast cancer Proteome 
ProteomicsComparative assessment of quantification methods for tumor tissue phosphoproteomics
The choice of quantification method is critical for study design and comparison of cancer phosphoproteomes. We comparatively assessed label-free quantification (LFQ), spike-in-SILAC (stable isotope labeling of amino acids in cell culture) and tandem mass tag (TMT) labeling techniques for quantitativ...
ORGANISM(S): Homo sapiens (Human) 
2022-08-09 | PXD030450 | Pride
Phosphoproteomics Tissue Ovarian cancer Quantification 
UnknownPhosphoproteome Analysis Using Two-Dimensional Electrophoresis Coupled with Chemical Dephosphorylation.
Not available
S-EPMC9562008 | biostudies-literature
UnknownComparative Assessment of Quantification Methods for Tumor Tissue Phosphoproteomics.
Not available
S-EPMC9366746 | biostudies-literature
ProteomicsIntegrated Proteomic Analysis of YCC-Derived Organoids
This dataset contains proteomic and phosphoproteomic profiles generated from YCC-derived organoid models. The study includes paired models established from the same patient-derived materials to investigate molecular differences associated with organoid growth and tumor-related biological features. I...
ORGANISM(S): Homo sapiens (Human) 
2026-06-19 | PXD076305 | Pride
Organoid 
ProteomicsProteomic and phosphoproteomic analysis of cell response to photon and particle irradiation
The growing number of particle treatment facilities worldwide and patients treated with particles instead of X-rays marks the upcoming rearrangement of modern radiotherapy. Especially for tumors being difficult to access and for tumors that are resistant to conventional X-ray treatment particle radi...
ORGANISM(S): Homo sapiens (Human) 
2017-03-20 | PXD004817 | Pride
Phosphoproteomics Dna-damage Silac Gelc-msms A549 Radiotherapy Ionizing radiation 
Proteomicswheat seed phosphoproteome under water deficit
Drought is one of the most serious abiotic stresses, under which the crop yield is significantly reduced. Elite winter wheat cultivar Henong 341 (Triticum aestivum L.) was grown in experimental fields of China Hebei province (116°37′23″E, 37°41′02″N) Two different treatment conditions were designed:...
ORGANISM(S): Triticum aestivum (Wheat) 
2016-07-09 | PXD000806 | Pride
Drought response and defense Phosphoproteome Bread wheat Water stress Seed development 
ProteomicsMouse Placenta Proteome and Phosphoproteome
TMT based quantification of protein abundance and phosphorylation state for developing mouse placenta. Timed-pregnant CD-1 mice were obtained from Charles Rivers Labs and dissected at e7.5 to extract the ectoplacental cones (EPCs) and at e9.5 to obtain the placenta as described by Martin and Cockrof...
ORGANISM(S): Mus Musculus (ncbitaxon:10090) 
2018-08-24 | MSV000082849 | MassIVE
ProteomicsComparative phosphoproteomic analysis of tomato genotypes with contrasting cadmium tolerance
A first insight into the effects of cadmium exposure on the phosphoproteome of tomato plants by performing a comparative analysis of tomato genotypes with contrasting cadmium tolerance.
ORGANISM(S): Solanum lycopersicum 
2021-08-11 | PXD024021 | Pride
Tomato Phosphoproteomics Crop engineering Cadmium-tolerance 
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