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Synaptic scaling is a form of homeostatic plasticity which allows neurons to adjust their action potential firing rate in response to chronic alterations in neural activity. Synaptic scaling requires profound changes in gene expression, but the relative contribution of local and cell-wide mechanisms...
ORGANISM(S): Rattus norvegicus (Rat) 
2021-07-09 | PXD020745 | Pride
Quek2008 - Genome-scale metabolic network of Mus musculus This model is described in the article: On the reconstruction of the Mus musculus genome-scale metabolic network model. Quek LE, Nielsen LK. Genome Inform 2008; 21: 89-100 Abstract: Genome-scale metabolic modelin...
2015-07-30 | MODEL1507180067 | BioModels
3' mRNA-seq was performed with QuantSeq 3' mRNA-Seq kit (Lexogen 015) according to the manufacturer’s recommendations. 3' mRNA-seq was done in biological triplicates (soma) or duplicates (neurites), using 260 ng of total RNA from neurites or soma of mESC-derived neurons per sample. Libraries were po...
ORGANISM(S): Mus musculus 
Spatiotemporal-controlled second messengers alter molecular interactions of central signaling nodes for ensuring physiological signal transmission. One prototypical second messenger molecule which modulates kinase signal transmission is the cyclic-adenosine monophosphate (cAMP). The main proteinogen...
ORGANISM(S): Homo sapiens (Human) 
2024-04-04 | PXD048869 | Pride
Chinese hamster ovary (CHO) cells have been widely employed for production of recombinant proteins (RP) for research and therapeutic purposes. Indeed, this expression system was used for production of most of approved antibodies (84%) in 2015-2018 period. The success of this cell line for RP product...
ORGANISM(S): Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) 
2021-05-04 | PXD021014 | Pride
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