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TranscriptomicsSubcellular expression profiling of the growth cones of retinal ganglion cells (RGC)
Cue-directed axon guidance depends partly on local translation in growth cones. Many mRNA transcripts are known to reside in developing axons yet little is known about their subcellular distribution or, specifically, which transcripts are in growth cones. Laser capture microdissection (LCM) was used...
ORGANISM(S): Xenopus laevis 
2010-11-23 | E-GEOD-25166 | biostudies-arrayexpress
TranscriptomicsmiRNA profiles of brain glioma stem cells and normal neural stem cells
A human microarray comprising 1658 human genome probes was used to evaluate the specific expression of miRNA between brian glioma stem cells (GSC) and normal neural stem cells(NSC). 2 total RNA samples are analyzed, brian glioma stem cells (GSC) and normal neural stem cells(NSC). cell type: brain g...
ORGANISM(S): Homo sapiens 
2014-07-30 | E-GEOD-41032 | biostudies-arrayexpress
TranscriptomicsNext Generation Sequencing Comparison of C57BL/6J and BC027072 -/- Eye Transcriptomes
We report the single base pair analysis of the ocular transcriptome from wild type and BC027072 knockout animals. Comparison was analyzed to understand gene expression changes in a mouse model for early onset retinal degeneration which phenocopies a human form of autosomal recessive retinitis pigmen...
ORGANISM(S): Mus musculus 
2015-02-03 | E-GEOD-63810 | biostudies-arrayexpress
TranscriptomicsTranscriptome profiles of brain glioma stem cells and normal neural stem cells
A human cDNA microarray comprising 29,187 human genome probes was used to evaluate the transcriptional changes between brian glioma stem cells (GSC) and normal neural stem cells(NSC). There were 6 samples that were analyzed, 3 samples were from glioma stem cells and the other 3 samples form normal n...
ORGANISM(S): Homo sapiens 
2014-07-30 | E-GEOD-41031 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of Drosophila developmental time series
Michelle N. Arbeitman, Eileen E. M. Furlong, Farhad Imam, Eric Johnson, Brian H. Null, Bruce S. Baker, Mark A. Krasnow, Matthew P. Scott, Ronald W. Davis and Kevin P. White. Gene Expression During the Life Cycle of Drosophila melanogaster, Science, 297: 2270-2275, 2002. This work can be accessed fro...
ORGANISM(S): Drosophila melanogaster 
2004-11-06 | E-FLYC-6 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of lager brewing yeast strain during industrial propagation and fermentation
Commercial brewing yeast strains are exposed to a number of potential stresses including oxidative stress. The aim of this investigation was to measure the physiological and transcriptional changes of yeast cells during full-scale industrial brewing processes with a view to determining the environme...
ORGANISM(S): Saccharomyces cerevisiae 
2008-06-16 | E-GEOD-9423 | biostudies-arrayexpress
GenomicsMapping Epigenomic Type-Specific Differences Occurring During Hematopoiesis [ChIP-Seq]
Formation of the blood from self-renewing hematopoietic stem cells to terminal lineages necessarily involves epigenomic modifications of the genome to control regulator and signature gene expression. By analysing the global expression profiles of hematopoietic stem cells (HSCs), in vivo differentiat...
ORGANISM(S): Homo sapiens 
2013-03-25 | E-GEOD-39538 | biostudies-arrayexpress
TranscriptomicsMapping Epigenomic Type-Specific Differences Occurring During Hematopoiesis
Formation of the blood from self-renewing hematopoietic stem cells to terminal lineages necessarily involves epigenomic modifications of the genome to control regulator and signature gene expression. By analysing the global expression profiles of hematopoietic stem cells (HSCs), in vivo differentiat...
ORGANISM(S): Homo sapiens 
2013-03-25 | E-GEOD-39229 | biostudies-arrayexpress
MetabolomicsClock regulation of metabolites reveals coupling between transcription and metabolism
The circadian clock is intricately connected with metabolism, however the precise details of these connections are incomplete. Here we used high temporal resolution metabolite profiling to determine circadian regulation of mouse liver and cell autonomous metabolism. In mouse liver, we found ~50% of ...
2017-04-05 | MTBLS292 | MetaboLights
TranscriptomicsMapping Epigenomic Type-Specific Differences Occurring During Hematopoiesis [RNA-Seq]
Formation of the blood from self-renewing hematopoietic stem cells to terminal lineages necessarily involves epigenomic modifications of the genome to control regulator and signature gene expression. By analysing the global expression profiles of hematopoietic stem cells (HSCs), in vivo differentiat...
ORGANISM(S): Homo sapiens 
2013-03-25 | E-GEOD-39537 | biostudies-arrayexpress
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