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ProteomicsIsoform-resolved Correlation Analysis Between mRNA Abundance Dynamics and Protein Level Degradation
We employed an optimized, sensitive DIA-MS method on a high-resolution Orbitrap platform and re-measured the proteomic samples used in a previous study, in which the heterogeneity of HeLa cells across different research labs was analyzed by a multi-omic approach. Using the same MS sample sets of all...
ORGANISM(S): Homo sapiens (Human) 
2020-03-11 | PXD014847 | Pride
Alternative splicing Protein turnover Protein isoform Dia mass spectrometry Correlation analysis Pulsed silac 
TranscriptomicsConservation of mRNA and protein expression during development of C. elegans
Spatiotemporal control of gene expression is crucial for development and subject to evolutionary changes. Although proteins are the final product of most genes, the developmental proteome of an animal has not yet been comprehensively defined, and the correlation between RNA and protein abundance dur...
ORGANISM(S): Caenorhabditis elegans 
2014-01-23 | E-GEOD-53359 | biostudies-arrayexpress
TranscriptomicsConcordant Regulation of Translation and mRNA Abundance for Hundreds of Targets of a Human microRNA
This SuperSeries is composed of the following subset Series: GSE18834: Human Argonaute Immunoaffinity Purification-associated RNA. GSE18835: mRNA abundance in HEK293T cells mock or miR-124 transfected. GSE18836: Translation Profiling +/- miR-124. GSE18837: Unamplified mRNA abundance in miR-124 and m...
ORGANISM(S): Homo sapiens 
2009-11-09 | E-GEOD-18889 | biostudies-arrayexpress
TranscriptomicsNeuCode metabolic labeling reveals a high correlation between mRNA and protein abundance during salt adaptation in S. cerevisiae.
Transcriptome profiling of yeast strains responding to 0.7M NaCl treatment for 30 or 60 minutes. This study identified affected genes under both conditions tested. Transcript and protein changes were compared to determine mRNAs contribution to protein levels during salt acclimation. Two-color fluore...
ORGANISM(S): Saccharomyces cerevisiae 
2013-12-21 | E-GEOD-53549 | biostudies-arrayexpress
TranscriptomicsGlobal Target mRNA Specification and Regulation by RNA-Binding Protein ZFP36/Tristetraprolin/TTP [PAR-CLIP]
Tristetraprolin/ZFP36/TTP and ELAVL1/HuR are two disease-relevant RNA-binding proteins (RBPs) that both interact with AU-rich sequences but have antagonistic roles. While ELAVL1 binding has been profiled in several studies, the precise in vivo binding specificity of ZFP36 has not been investigated o...
ORGANISM(S): Homo sapiens 
2013-12-24 | E-GEOD-53184 | biostudies-arrayexpress
TranscriptomicsRNA Abundance in E. coli
Steady-state abundance of known and predicted E. coli mRNAs at single-gene resolution by using two-color fluorescent DNA microarrays. Set of arrays organized by shared biological context, such as organism, tumors types, processes, etc. Computed
ORGANISM(S): Escherichia coli 
2005-09-09 | E-GEOD-3265 | biostudies-arrayexpress
ProteomicsOn the relationship of protein and mRNA dynamics in vertebrate embryonic development
How the fertilized egg develops the anatomy of an adult ultimately must be explained at the biochemical level. Deeply connected to the anatomy is the complement of proteins and RNAs expressed during embryogenesis. The relationship of mRNA and respective protein expression dynamics during development...
ORGANISM(S): Xenopus laevis (African clawed frog) 
2015-10-20 | PXD002349 | Pride
Protein dynamics Mrna dynamics Xenopus Embryonic development 
UnknownCorrelation of Cry1Ac mRNA and protein abundance in transgenic Gossypium hirsutum plant.
Not available
S-EPMC8141090 | biostudies-literature
GenomicsUnraveling the Complex Relationship Between mRNA and Protein Abundance: A Machine Learning-Based Approach for Imputing Protein Levels from RNA-seq Data
Unraveling the Complex Relationship Between mRNA and Protein Abundance: A Machine Learning-Based Approach for Imputing Protein Levels from RNA-seq Data
PRJNA1015644 | ENA
UnknownIsoform-resolved correlation analysis between mRNA abundance regulation and protein level degradation.
Not available
S-EPMC7073818 | biostudies-literature
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