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MetabolomicsDefective mitochondrial COX1 translation due to loss of COX14 function triggers ROS-induced inflammation in liver
Mitochondrial oxidative phosphorylation (OXPHOS) fuels cellular ATP demands. OXPHOS defects lead to severe human disorders with unexplained tissue specific pathologies. Mitochondrial gene expression is essential for OXPHOS biogenesis since core subunits of the complexes are mitochondrial-encoded. CO...
2024-07-19 | MTBLS9823 | MetaboLights
ProteomicsDefective mitochondrial translation due to loss of COX14 function triggers ROS-induced inflammation in liver
Mitochondrial oxidative phosphorylation (OXPHOS) fuels cellular ATP demands. OXPHOS defects lead to severe human disorders with unexplained tissue specific pathologies. Mitochondrial gene expression is essential for OXPHOS biogenesis since core subunits of the complexes are mitochondrial-encoded. CO...
ORGANISM(S): Mus musculus (Mouse) 
2024-07-25 | PXD041783 | Pride
Mouse Ros Liver Cox14 
UnknownDefective mitochondrial COX1 translation due to loss of COX14 function triggers ROS-induced inflammation in mouse liver.
Not available
S-EPMC11319346 | biostudies-literature
GenomicsDefective mitochondrial COX1 translation due to loss of COX14 function triggers ROS-induced inflammation in mouse liver
Defective mitochondrial COX1 translation due to loss of COX14 function triggers ROS-induced inflammation in mouse liver
PRJNA1122218 | ENA
TranscriptomicsDefective mitochondrial COX1 translation due to loss of COX14 function triggers ROS-induced inflammation in mouse liver
Mitochondrial oxidative phosphorylation (OXPHOS) fuels cellular ATP demands. OXPHOS defects lead to severe human disorders with unexplained tissue specific pathologies. Mitochondrial gene expression is essential for OXPHOS biogenesis since core subunits of the complexes are mitochondrial-encoded. CO...
ORGANISM(S): Mus musculus 
2024-06-11 | GSE269535 | GEO
UnknownA CMC1-knockout reveals translation-independent control of human mitochondrial complex IV biogenesis.
Not available
S-EPMC5331208 | biostudies-literature
UnknownMulti-Omics Analysis of a Spontaneous Type 2 Diabetes Model in <i>Myodes rufocanus</i> and Its Underlying Mechanisms.
Not available
S-EPMC12898206 | biostudies-literature
UnknownMrpL35, a mitospecific component of mitoribosomes, plays a key role in cytochrome c oxidase assembly.
Not available
S-EPMC5683760 | biostudies-literature
UnknownCox1 mutation abrogates need for Cox23 in cytochrome c oxidase biogenesis.
Not available
S-EPMC5354592 | biostudies-literature
UnknownAneuploidy-driven gene expression profiling in human blastocysts: insights from RNA-Seq analysis.
Not available
S-EPMC11950541 | biostudies-literature
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