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ProteomicsEvaluating cPILOT Performance on Orbitrap Instruments
A global cPILOT assay developed on an Orbitrap Velos instrument was transitioned to an Orbitrap Fusion Lumos instrument. Parameters such as the LC gradient, m/z isolation window, dynamic exclusion, targeted mass analyses, and SPS-N were optimized. The number of proteins identified on the Fusion Lumo...
ORGANISM(S): Mus musculus (Mouse) 
2021-09-08 | PXD012133 | Pride
Proteomics Fusion lumos Alzheimer's disease Multiplexing Cpilot 
UnknownAutomated Sample Multiplexing by using Combined Precursor Isotopic Labeling and Isobaric Tagging (cPILOT).
Not available
S-EPMC9153850 | biostudies-literature
UnknownHigh-throughput endogenous measurement of S-nitrosylation in Alzheimer's disease using oxidized cysteine-selective cPILOT.
Not available
S-EPMC4904844 | biostudies-literature
ProteomicsInsulin Resistance in a Type 1 Diabetes Rat Model
A automated 32-plex cPILOT chemical labeling strategy was utilized to identify proteome changes in type 1 diabetes in rats. We utilized an Orbitrap Fusion Lumos mass spectrometer to analyze 8 fractions in technical triplicates where proteins were quantified using Tandem Mass Tag pro reagents (16-ple...
ORGANISM(S): Rattus norvegicus (Rat) 
2025-05-26 | PXD033761 | Pride
Multiplexing Type 1 diabetes Insulin resistance Cpilot 
ProteomicsQuantitative Proteomics to Study Aging in Rabbit Liver
This project describes the quatitative changes in the rabbit liver in response of increasing age. Quantitative proteomics workflow was used to track metabolic changes that occur in the rabbit liver with elderly. Three age groups (young, middle, and old age rabbits were quantitatively compared and en...
ORGANISM(S): Oryctolagus cuniculus (Rabbit) 
2020-03-19 | PXD013220 | Pride
Metabolism Enhanced multiplexing Liver Cpilot Quantitative proteomics Aging Rabbit 
UnknownIn Vivo Fast Photochemical Oxidation of Proteins Using Enhanced Multiplexing Proteomics.
Not available
S-EPMC7815197 | biostudies-literature
UnknownEvaluating Combined Precursor Isotopic Labeling and Isobaric Tagging Performance on Orbitraps To Study the Peripheral Proteome of Alzheimer's Disease.
Not available
S-EPMC7932850 | biostudies-literature
UnknownIncreased N,N-Dimethyl Leucine Isobaric Tag Multiplexing by a Combined Precursor Isotopic Labeling and Isobaric Tagging Approach.
Not available
S-EPMC6314838 | biostudies-literature
UnknownQuantitative proteomics to study aging in rabbit liver.
Not available
S-EPMC7138690 | biostudies-literature
UnknownDataset of quantitative proteomic analysis to understand aging processes in rabbit liver.
Not available
S-EPMC7262418 | biostudies-literature
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