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GenomicsCTD-ILD BALF and blood scRNA-seq data
we analyzed immune cells in BALF and blood samples from patients with newly developed CTD-ILD using single-cell RNA sequencing. We aimed to clarify the pathogenesis of SS-ILD and investigate its characteristics in terms of the distribution and gene expression in BALF and blood immune cells in detail...
EGAS00001007539 | EGA
Genomics2a8d9e3c-3a68-4472-b4b7-40985237aca5 - samples
CTD-ILD BALF and blood scRNA-seq dataset consists of single-cell transcriptome data of bronchoalveolar lavage fluid (BALF) and blood derived from 30 connective tissue disease-associated interstitial lung disease (CTD-ILD) and 12 idiopathic interstitial pneumonia (IIP) patients.
EGAD00001011334 | EGA
TranscriptomicsSingle-Cell RNA Sequencing of PBMCs from Clinically Stable Connective Tissue Disease-associated Interstitial Lung Disease (CTD-ILD) Patients after Lung Transplantation
Connective tissue disease–associated interstitial lung disease (CTD-ILD) is a major indication for lung transplantation in patients with advanced disease. Here, we performed single-cell RNA sequencing (scRNA-seq) of peripheral blood mononuclear cells (PBMCs) from two clinically stable CTD-ILD patien...
ORGANISM(S): Homo sapiens 
2026-03-19 | GSE324889 | GEO
ProteomicsA proteomics workflow reveals predictive autoantigens in idiopathic pulmonary fibrosis (cohort 2)
Rationale: The diagnosis of idiopathic pulmonary fibrosis (IPF) requires exclusion of an underlying autoimmune disease, as present in interstitial lung diseases associated with connective tissue diseases (CTD-ILD). The prevalence of autoantibodies in IPF patients is currently unknown. Objectives: An...
ORGANISM(S): Homo sapiens (Human) 
2021-02-22 | PXD024123 | Pride
Ipf Ctd-ild Clinical proteomics Autoantibodies Autoimmunity Lung fibrosis 
ProteomicsA proteomics workflow reveals predictive autoantigens in idiopathic pulmonary fibrosis (cohort 1)
Rationale: The diagnosis of idiopathic pulmonary fibrosis (IPF) requires exclusion of an underlying autoimmune disease, as present in interstitial lung diseases associated with connective tissue diseases (CTD-ILD). The prevalence of autoantibodies in IPF patients is currently unknown. Objectives: An...
ORGANISM(S): Homo sapiens (Human) 
2021-02-22 | PXD024113 | Pride
Ipf Ctd-ild Clinical proteomics Autoantibodies Autoimmunity Lung fibrosis 
UnknownUnderstanding Interstitial Lung Diseases Associated with Connective Tissue Disease (CTD-ILD): Genetics, Cellular Pathophysiology, and Biologic Drivers.
Not available
S-EPMC9917355 | biostudies-literature
UnknownPolydatin-curcumin formulation alleviates CTD-ILD-like lung injury in mice via GABBR/PI3K/AKT/TGF-β pathway.
Not available
S-EPMC12176778 | biostudies-literature
UnknownAntifibrotic drugs in connective tissue disease-related interstitial lung disease (CTD-ILD): from mechanistic insights to therapeutic applications.
Not available
S-EPMC7813437 | biostudies-literature
GenomicsPolydatin-Curcumin Formulation Alleviates CTD-ILD-like Lung Injury in Mice
Polydatin-Curcumin Formulation Alleviates CTD-ILD-like Lung Injury in Mice
PRJEB89919 | ENA
UnknownClinical, Serological, and Histopathological Similarities Between Severe COVID-19 and Acute Exacerbation of Connective Tissue Disease-Associated Interstitial Lung Disease (CTD-ILD).
Not available
S-EPMC7566417 | biostudies-literature
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