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TranscriptomicsProfiling transcriptomic response of Enchytraeus albidus to Cu and Ni: Comparison with Cd and Zn
Metals, including copper (Cu) and nickel (Ni) are among the most common contaminants in soils in Europe. Although their effects are relatively well known regarding survival and reproduction of soil invertebrates, their modes of action in these organisms are still poorly studied. Enchytraeus albidus ...
ORGANISM(S): Enchytraeus albidus 
2013-12-31 | E-GEOD-47662 | biostudies-arrayexpress
TranscriptomicsRNA-seq of Arabidopsis spl7 identifies two genes required for copper acquisition and a copper dependence of iron homeostasis
The transition metal copper (Cu) is an essential element for all living organisms. In plants, Cu plays key roles in electron transport chains of chloroplasts and mitochondria, as well as in cell wall metabolism, ethylene perception, molybdenum cofactor synthesis and oxidative stress protection. Beca...
ORGANISM(S): Arabidopsis thaliana 
2013-10-14 | E-GEOD-24696 | biostudies-arrayexpress
ProteomicsArabidopsis AGO1 interactome under Cu deficiency and Cu sufficiency
In this project we look for AGO1 protein interactors in pAGO1-TST-AGO1 (Col-0) transgenic plants grown under Cu deficiency or under cu sufficiency. TST-AGO1 complexes were affinity purified and proteins were identified by tandem MS.
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2025-11-17 | PXD057108 | Pride
Cu Arabidopsis Ago1 
TranscriptomicsTranscription profiling of Stickleback liver exposed to Cu, DbA (Dibezanthracene), EE2 (Ethinyl-estradiol) or relevant controls
Stickleback were exposed to Cu, DbA (Dibezanthracene), EE2 (Ethinyl-estradiol) or relevant controls. Pooled liver tissue from treatment groups exposed to different doses were arrayed versus a common reference.
ORGANISM(S): Gasterosteus aculeatus 
2009-07-10 | E-MAXD-43 | biostudies-arrayexpress
TranscriptomicsThe Arabidopsis copper transport protein COPT2 and the responses under copper and iron deficiency.
Copper and iron are essential micronutrients for most living organisms because they participate as cofactors in biological processes including respiration, photosynthesis and oxidative stress protection. In many eukaryotic organisms, including yeast and mammals, copper and iron homeostases are highl...
ORGANISM(S): Arabidopsis thaliana 
2013-06-05 | E-GEOD-42642 | biostudies-arrayexpress
ProteomicsProtein stability changes reveal targets of pyrithione-induced Cu toxicity in E. coli
The biological activities of metals and ionophores have brought them to the forefront as potent antimicrobial and anticancer agents. However, the biological mechanisms behind these activities are not well understood. This work describes the first utilization of proteome-wide measurements of protein ...
ORGANISM(S): Escherichia coli 
2020-12-08 | PXD021198 | Pride
Cu toxicity Protein stability Pyrithione E. coli 
TranscriptomicsSystems analysis of Chlamydomonas Cu nutrition reveals connections between Cu and multiple O2-dependent metabolic steps
We used digital gene expression (NlaIII sequence tags) and RNA-Seq to compare the transcriptomes of Cu-replete vs. Cu–deficient Chlamydomonas wild-type cells to reveal dozens of mRNAs whose abundance is modified. Half of the corresponding genes are targets of CRR1, a master regulator of nutritional ...
ORGANISM(S): Chlamydomonas reinhardtii 
2011-10-23 | E-GEOD-25124 | biostudies-arrayexpress
no omics definedTranscription profiling of copper-stressed Pseudomonas aeruginosa
Anthropogenic pollution has increased the levels of heavy metals in the environment. Bacterial populations continue to thrive in highly polluted environments and bacteria must have mechanisms to counter heavy metal stress. We chose to examine the response of the environmentally-relevant organism P...
ORGANISM(S): Pseudomonas aeruginosa 
2007-10-24 | E-GEOD-4152 | biostudies-arrayexpress
GenomicsSaccharomyces cerevisiae strain:CU-TPD4
Genomic analysis and overexpressing acetyl-CoA carboxylase of oleaginous Saccharomyces cerevisiae CU-TPD4 for enhanced lipid production from agricultural residues
PRJNA1184202 | ENA
GenomicsCu contaminated soil metagenome
Cu contaminated soil metagenome Targeted loci environmental
PRJNA609894 | ENA
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