Sort   by:  
 Page size 
GenomicsVirulence regulator EspR of Mycobacterium tuberculosis is a nucleoid-associated protein
The principal virulence determinant of Mycobacterium tuberculosis (Mtb), the ESX-1 protein secretion system, is positively controlled at the transcriptional level by EspR. Depletion of EspR reportedly affects a small number of genes, both positively or negatively, including a key ESX-1 component, th...
ORGANISM(S): Mycobacterium tuberculosis 
2012-04-02 | E-GEOD-35149 | biostudies-arrayexpress
ProteomicsCulture filtrate of Mycobacterium tuberculosis clinical isolate S169 DIA
Phagosome acidification is one of the challenges faced by Mycobacterium tuberculosis during infection. This intracellular pathogen is known to adapt to its stressful environment through stress response pathways and by secreting proteins to modify the host immune response for survival and proliferati...
ORGANISM(S): Mycobacterium tuberculosis H37Rv 
2026-02-13 | PXD073840 | Pride
Tuberculosis Stress Dia 
ProteomicsProteomic profiling of Mycobacterium tuberculosis culture filtrate identifies novel O-glycosylated proteins
Integrative evaluation of M. tuberculosis culture filtrate proteins and O-glycosylation profile analysis. Shotgun analysis of culture filtrate proteins of M. tuberculosis based on a liquid nano-HPLC tandem mass spectrometry and a label-free spectral counting normalization approach for protein quanti...
ORGANISM(S): Mycobacterium Tuberculosis (ncbitaxon:1773) 
2019-08-08 | MSV000084184 | MassIVE
ProteomicsCulture filtrate of Mycobacterium tuberculosis clinical isolate S169
Phagosome acidification is one of the challenges faced by Mycobacterium tuberculosis during infection. This intracellular pathogen is known to adapt to its stressful environment though stress response pathways and by secreting proteins to modify the host immune response for survival and proliferatio...
ORGANISM(S): Mycobacterium tuberculosis 
2025-10-04 | PXD068720 | Pride
Acid stress Tuberculosis Heterogenous Persister Vbnr Tb 
TranscriptomicsTranscription profiling of Mycobacterium bovis with pYUB412 and pRD1-2F9 genes knocked-in to investigate the ESX-1 secretion system
The dedicated secretion system ESX-1 of Mycobacterium tuberculosis encoded by the extended RD1 region (extRD1) assures export of the ESAT-6 protein and its partner, the 10 kDa culture filtrate protein CFP-10, and is missing from the vaccine strains M.bovis BCG and M.microti. Here, we systematically ...
ORGANISM(S): Mycobacterium bovis 
2007-01-30 | E-BUGS-31 | biostudies-arrayexpress
ProteomicsMycobacterium tuberculosis culture filtrate LC-MS/MS
Triplicate culture filtrate samples of normal (log phase) and PBS cultured (starvation) M. tuberculosis were separated by SDS-PAGE, and 10 bands were excised from each lane after staining with Coomassie R-250. In-gel trypsin digestion was performed on gel bands followed by nanoLC. Eluting peptides w...
ORGANISM(S): Mycobacterium tuberculosis H37Rv 
2013-01-24 | PXD000111 | Pride
Tuberculosis Culture filtrate Lc-ms/ms 
ProteomicsProteomic profiling of culture filtrates from M.tuberculosis H37Rv
In this report, a novel tandem cascade of biomimetic affinity chromatography (BiAC) system was used to fractionate the culture filtrate proteins (CFPs) of M. tuberculosis (MTB) prior to LC-MS/MS analysis. Consequently, in fractionations by 6 BiAC columns, 541 proteins from CFPs were identified using...
ORGANISM(S): Mycobacterium tuberculosis H37Rv Salmonella enterica subsp. enterica serovar Untypable str. 83332 
2018-07-05 | PXD005290 | Pride
Biomimetic affinity chromatography Low-abundant proteins Culture filtrate proteins of mycobacterium tuberculosis Extreme biochemical characteristics proteins 
Proteomicscell lysate of Mycobacterium tuberculosis clinical isolate S169
Phagosome acidification is one of the challenges faced by Mycobacterium tuberculosis during infection. This intracellular pathogen is known to adapt to its stressful environment though stress response pathways and by secreting proteins to modify the host immune response for survival and proliferatio...
ORGANISM(S): Mycobacterium tuberculosis 
2025-10-04 | PXD068623 | Pride
Acid stress Tuberculosis Heterogenous Persister Vbnr Tb 
ProteomicsMycobacterium tuberculosis extracellular vesicle proteome
Tuberculosis is a common infectious disease mostly caused by Mycobacterium tuberculosis. M. tuberculosis have been shown to release extracellular vesicles (EVs) containing immunologically active molecules. However, only limited number of proteins has been identified in M. tuberculosis EVs. We presen...
ORGANISM(S): Mycobacterium tuberculosis H37Rv 
2015-07-30 | PXD001160 | Pride
Exosomes Mycobacterium tuberculosis Extracellular vesicles Outer membrane vesicles Bacteria 
ProteomicsPhosphorylation of CFP10 modulates Mycobacterium tuberculosis virulence
Virulence effectors secreted by Mycobacterium tuberculosis (Mtb) help subvert host immune mechanisms and, therefore, are critical for establishing infection and pathogenesis. However, knowledge in terms of signaling mechanisms that modulate the secretion of virulence factors is sparse. We performed ...
ORGANISM(S): Mycobacterium tuberculosis H37Rv 
2023-09-22 | PXD045586 | Pride
Cfp10 Secretion Virulence Pkna Tuberculosis Pknb Phosphorylation Esat6 
Sort   by:  
 Page size