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TranscriptomicsMyelodysplastic syndrome: NUP98-HoxD13 (NHD13) expression effect on hematopoietic stem cells
Analysis of Lin-c-Kit+Sca-1- haematopoietic stem cells (HSCs) expressing the Nup98-HoxD13 (NHD13) fusion gene. NHD13 induces myelodysplastic syndrome (MDS) in mice. Results provide insight into the molecular basis of the myelodysplastic phenotype WT mouse HSCs were compared to an NHD13 mutant sequen...
ORGANISM(S): Mus musculus 
2016-07-03 | E-GEOD-66264 | biostudies-arrayexpress
ProteomicsA systems immunology study comparing innate and adaptive immune responses in adults to COVID-19 mRNA (BNT162b2/mRNA-1273) and adenovirus vectored vaccines (ChAdOx1-S)
We longitudinally profiled plasma proteomes in 54 adults vaccinated with the BNT162b2 (Pfizer-BioNTech) or ChAdOx1-S (Oxford-AstraZeneca) vaccines. Blood was collected pre-vaccination (V0) and 1-7 days after the 1st doses (BNT162b2 or mRNA-1273, V1) to assess innate and early adaptive responses. We ...
ORGANISM(S): Homo sapiens (Human) 
2023-03-01 | PXD036608 | Pride
Sars-cov-2 Proteomics Plasma Vaccination Covid-19 vaccine 
UnknownPersistence With Conventional Triple Therapy Versus a Tumor Necrosis Factor Inhibitor and Methotrexate in US Veterans With Rheumatoid Arthritis.
Not available
S-EPMC6207907 | biostudies-literature
UnknownComparative bio-accessibility, bioavailability and bioequivalence of quercetin, apigenin, glucoraphanin and carotenoids from freeze-dried vegetables incorporated into a baked snack versus minimally processed vegetables: Evidence from in vitro models and a human bioavailability study.
Not available
S-EPMC6189524 | biostudies-literature
UnknownLong access heroin self-administration significantly alters gut microbiome composition and structure.
Not available
S-EPMC10927763 | biostudies-literature
TranscriptomicsEthanol exposure disrupts extraembryonic microtubule cytoskeleton and embryonic blastomere cell adhesion, producing epiboly and gastrulation defects
Gene expression was measured using microarrays in 8 hour postfertilization embryos, comparing control versus ethanol-treated (2 to 8 hours postfertilization) embryos. This experiment was performed to determine the gene expression changes that occur in response to ethanol treatment as a model of feta...
ORGANISM(S): Danio rerio 
2014-07-09 | E-GEOD-48380 | biostudies-arrayexpress
UnknownImmune Responses to Circulating and Vaccine Viral Strains in HIV-Infected and Uninfected Children and Youth Who Received the 2013/2014 Quadrivalent Live-Attenuated Influenza Vaccine.
Not available
S-EPMC4831981 | biostudies-literature
UnknownSpatial proteomic characterization of HER2-positive breast tumors through neoadjuvant therapy predicts response.
Not available
S-EPMC8713949 | biostudies-literature
UnknownInherited mutations in 17 breast cancer susceptibility genes among a large triple-negative breast cancer cohort unselected for family history of breast cancer.
Not available
S-EPMC4302212 | biostudies-literature
ProteomicsPolyamines and eIF5A hypusination modulate mitochondrial respiration and macrophage activation
How cells adapt metabolism to meet demands is an active area of interest across biology. Amongst a broad range of functions, the polyamine spermidine is needed to hypusinate the translation factor eukaryotic initiation factor 5A (eIF5A). We show here that hypusinated eIF5A (eIF5AH) promotes the effi...
ORGANISM(S): Mus musculus (Mouse) 
2019-05-24 | PXD013443 | Pride
Proteomics Macrophage Polyamine Eif5a 
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