Sort   by:  
 Page size 
MetabolomicsThe genetic origin of evolidine, the first cyclopeptide discovered in plants, and related orbitides

Cyclic peptides are reported to have antibacterial, antifungal and other bioactivities. Orbitides are a class of cyclic peptide that are small, head-to-tail cyclized, composed of proteinogenic amino acids, and lack disulfide bonds; they are also known in several genera of the plant family Rutacea...

2020-10-14 | MTBLS1963 | MetaboLights
TranscriptomicsInhibition of Staphylococcus aureus biofilm formation by gurmarin, a plant-derived cyclic peptide
Staphylococcus aureus is an opportunistic pathogen capable of causing various infections ranging from superficial skin infections to life-threatening severe diseases, including pneumonia and sepsis. This bacterium is attached to biotic and abiotic surfaces and forms biofilms that are resistant to co...
ORGANISM(S): Staphylococcus aureus 
2022-09-21 | E-MTAB-12154 | biostudies-arrayexpress
ProteomicsDevelopment of Proteome Derived Cyclic Peptide Libraries via Ortho Phthalaldehyde Assisted Cyclization
This dataset contains raw LC–MS/MS data and associated search results generated for the identification and characterization of proteome-derived cyclic peptides produced via ortho-phthalaldehyde (OPA)-mediated macrocyclization. Cysteine-containing peptides derived from human proteome digests were sel...
ORGANISM(S): Homo sapiens (Human) 
2026-09-03 | PXD074548 | Pride
Cyclic peptide library Mass spectrometry Ortho-phthalaldehyde (opa) Igg-binding peptide Protein recognition 
GenomicsRapid discovery of cyclic peptide protein aggregation inhibitors through continuous selection HTS data
Rapid discovery of cyclic peptide protein aggregation inhibitors through continuous selection HTS data
PRJNA1170358 | ENA
TranscriptomicsCollagen-binding C-type natriuretic peptide enhances chondrogenesis and osteogenesis
To enhance local drug delivery and therapeutic efficacy, we developed a novel synthetic protein by fusing a collagen-binding domain (CBD) to C-type natriuretic peptide (CNP), termed CBD-CNP. CBD-CNP localized to collagen-rich tissues and promoted bone elongation.
ORGANISM(S): Mus musculus 
2025-12-05 | E-MTAB-16154 | biostudies-arrayexpress
GenomicsA Natural Cyclic Peptide Enhances Cytotoxic Th9 Differentiation and Antitumor Immunity
A Natural Cyclic Peptide Enhances Cytotoxic Th9 Differentiation and Antitumor Immunity
PRJNA1252720 | ENA
TranscriptomicsMOTS-c: A Novel Peptide Encoded by a Short Mitochondrial Open Reading Frame Regulates Metabolic Homeostasis
Mitochondria are known to be functional organelles, but their role as a signaling unit is increasingly being appreciated. The recent identification of a short open reading frame (sORF) in the mitochondrial DNA (mtDNA) that encodes a signaling peptide, humanin, suggests the possible existence of addi...
ORGANISM(S): Homo sapiens 
2015-03-07 | E-GEOD-65068 | biostudies-arrayexpress
ProteomicsA cyclic peptide toolkit reveals mechanistic principles of peptidylarginine deiminase IV (PADI4) regulation
Deregulation of the peptidylarginine deiminase PADI4 promotes the development of autoimmunity, cancer, atherosclerosis and age-related tissue fibrosis. Genetic or pharmacological PADI4 inhibition is therapeutically efficacious in mice but no clinically relevant inhibitors exist to date. PADI4 additi...
ORGANISM(S): Mus musculus (Mouse) 
2025-05-06 | PXD048807 | Pride
Deiminase Cyclic-peptide Modulator Padi4 
OtherRapid discovery of cyclic peptide protein aggregation inhibitors through continuous selection HTS data
We report a new platform for the rapid phenotypic selection of protein aggregation inhibitors from genetically encoded cyclic peptide libraries in E. coli based on phage-assisted continuous evolution (PACE). Here, we developed a new PACE-compatible selection for protein aggregation inhibition and em...
ORGANISM(S): Inovirus M13 
2024-10-25 | GSE279094 | GEO
ProteomicsNIST mAb High Throughput Peptide Mapping With Cyclic IM-MS
Peptide mapping datasets for NIST mAb using 15-s and 1-min LC gradient separations coupled to Cyclic IM-MS.
ORGANISM(S): Antibody Standard 
2025-06-15 | MSV000098206 | MassIVE
Sort   by:  
 Page size