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Mitochondria control bioenergetics and cell fate decisions, but whether they also participate in extra-organelle signaling is not understood. Here, we show that interference with cyclophilin D (CypD), a mitochondrial matrix protein and apoptosis regulator, causes accelerated cell proliferation and ...
ORGANISM(S): Mus musculus 
We aimed at identify variants of the mitochondrial Cyclophilin D from total lysates of human skin fibroblasts and murine tissues. Total lysates were loaded onto SDS-PAGE stained with MS-compatible Coomassie and bands around 19 and 18 kDa were manually excised. In fact in Western blots analysis of Cy...
ORGANISM(S): Mus musculus (Mouse) Homo sapiens (Human) 
2025-05-07 | PXD057203 | Pride
we examine the genes expression after activation of mitoflash. The MEF were expressed with CypD or treated with paraquat and mastoparan. RNA was harvested using Trizol reagent. Illumina TruSeq RNA Sample Prep Kit was used with 1 ug of total RNA for the construction of sequencing libraries.RNA libra...
ORGANISM(S): Mus musculus 
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