Sort   by:  
 Page size 
ProteomicsHDAC6 interacting proteins under different stresses
we treated MFE cell (WT and HDAC6 KO) with different stresses, incluing MG132, CytoD and IAV infection, then use home-made HDAC6 antibody to capture HDAC6 and coimmunoprecipitate its interacting proteins.
ORGANISM(S): Mus musculus (Mouse) 
2023-10-17 | PXD038816 | Pride
Cytod Iav Hdac6 Mg132 
TranscriptomicsOsteogenic programming of adipose-derived mesenchymal stem cells using a fungal metabolite that suppresses the Polycomb protein EZH2
We report genome-wide expression changes that occur in adipose-derived mesenchymal stem cells upon treatment with CytoD cytoskeletal drug. mRNA-Seq analysis shows that CytoD-treated samples cluster together. In addition, we also see that cells treated with CytoD show upregulation of osteogenic marke...
ORGANISM(S): Homo sapiens 
2017-03-21 | GSE96788 | GEO
UnknownOsteogenic Stimulation of Human Adipose-Derived Mesenchymal Stem Cells Using a Fungal Metabolite That Suppresses the Polycomb Group Protein EZH2.
Not available
S-EPMC5788881 | biostudies-literature
UnknownValidation of Osteogenic Properties of Cytochalasin D by High-Resolution RNA-Sequencing in Mesenchymal Stem Cells Derived from Bone Marrow and Adipose Tissues.
Not available
S-EPMC6096350 | biostudies-literature
GenomicsNuclear actin structure regulates chromatin accessibility [ATAC-seq]
Polymerized B-actin may provide a structural basis for chromatin accessibility and actin transport into the nucleus can guide mesenchymal stem cell (MSC) differentiation. Using MSC, we show that using CK666 to inhibit Arp2/3 directed secondary actin branching results in decreased nuclear actin struc...
ORGANISM(S): Mus musculus 
2024-04-12 | GSE242944 | GEO
TranscriptomicsNuclear actin structure regulates chromatin accessibility [RNA-seq]
Polymerized b-actin may provide a structural basis for chromatin accessibility. Nuclear actin transport into the nucleus can determine mesenchymal stem cell (MSC) differentiative outcomes through regulated control of gene expression. Using MSC, we show that inhibiting Arp2/3 directed secondary actin...
ORGANISM(S): Mus musculus 
2024-04-12 | GSE242943 | GEO
TranscriptomicsStudy on the effects of cytoskeletal modifying compounds on stem cell differentiation
We report genome-wide expression changes that occur in mouse bone marrow-derived mesenchymal stem cells treated in triplicate for 24 hours with or without Cytochalasin D and/or CK666. mRNA-Seq analysis shows that both cell surface and the nucleus undergo phenotypic changes. Cytochalasin D enhanced e...
ORGANISM(S): Mus musculus 
2016-12-30 | GSE89132 | GEO
UnknownDynamic rearrangement of F-actin is required to maintain the antitumor effect of trichostatin A.
Not available
S-EPMC4028200 | biostudies-literature
UnknownMacrophage solubilization and cytotoxicity of indium-containing particles in vitro.
Not available
S-EPMC3807620 | biostudies-literature
UnknownGPR30-mediated estrogenic regulation of actin polymerization and spatial memory involves SRC-1 and PI3K-mTORC2 in the hippocampus of female mice.
Not available
S-EPMC6515707 | biostudies-literature
Sort   by:  
 Page size