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ProteomicsExit of spore dormancy transforms the yeast cytoplasm and the solubility of its proteome
The biophysical properties of the cytoplasm are a major determinant of key cellular processes. Yeasts produce dormant spores that can withstand extreme conditions. We show that spores exhibit extraordinary biophysical properties, including a highly viscous and acidic cytosol. These conditions alter ...
ORGANISM(S): Saccharomyces cerevisiae (Baker's yeast) 
2023-03-14 | PXD035403 | Pride
Cytoplasm Cell dormancy Protein phosphorylation Protein solubility 
GenomicsEukaryotic cytoplasm is widely structured via mesoscale condensates
Eukaryotic cytoplasm is widely structured via mesoscale condensates
PRJNA973094 | ENA
TranscriptomicsDeep Sequencing of Human Nuclear and Cytoplasmic Small RNAs Reveals an Unexpectedly Complex Subcellular Distribution of miRNAs and tRNA 3' Trailers
Background: MicroRNAs (miRNAs) are 22-nt small non-coding regulatory RNAs that have generally been considered to regulate gene expression at the post-transcriptional level in the cytoplasm. However, recent studies have reported that some miRNAs localize to and function in the nucleus. Methodology/Pr...
ORGANISM(S): Homo sapiens 
2010-07-14 | E-GEOD-22918 | biostudies-arrayexpress
GenomicsIRF3 attenuates hypoxia signaling by retaining HIF-α in the cytoplasm
IRF3 attenuates hypoxia signaling by retaining HIF-α in the cytoplasm
PRJNA1369539 | ENA
ProteomicsIdentification of lncRNA CALA-dependent protein interaction partners of G3BP1 in the cytoplasm
We previously identified the stimuli-responsive lncRNA CALA to impact endothelial cell function and identified G3BP1 as a main interaction partner of CALA in the cytoplasm of human umblical vein endothelial cells (HUVECs). To uncover the role of the lncRNA CALA in G3BP1-RNPs in the cytoplasm, we pur...
ORGANISM(S): Homo sapiens (Human) 
2022-07-04 | PXD033517 | Pride
Lncrna-dependent protein/protein interaction 
ProteomicsSFPQ interacted proteins in HEK293T nucleus and cytoplasm
Splicing factor proline and glutamine rich (SFPQ), DNA- and RNA binding protein, is crucial in various nuclear processes, including paraspeckle formation, miRNA synthesis and specially in transcription regulation. In addition, SFPQ play a role in the innate immune response to viruses, including DNA ...
ORGANISM(S): Homo sapiens (Human) 
2019-01-10 | PXD011865 | Pride
Sfpq  hek2893t  nucleus  cytoplasm 
GenomicsDNA:cytoplasm ratio defines an upper limit to cell size [array]
DNA:cytoplasm ratio defines an upper limit to cell size [array]
PRJNA435760 | ENA
GenomicsDNA:cytoplasm ratio defines an upper limit to cell size [RNA-seq]
DNA:cytoplasm ratio defines an upper limit to cell size [RNA-seq]
PRJNA434318 | ENA
TranscriptomicsSubcellular distribution of RNAs in HeLa cells
HeLa cells were fractioned in nucleus and cytoplasm to investigate the subcellular distribution of lncRNAs. Two-condition experiment, nuclear fraction vs. cytoplasmatic fraction from HeLa cells. Biological replicates: 2 with dye-swap
ORGANISM(S): Homo sapiens 
2015-06-30 | E-GEOD-62985 | biostudies-arrayexpress
TranscriptomicsMicroarray analysis of the oocyte quality
Microarray analysis was performed in ooplast samples to identify gene expression profiles associated with the embryo capacity to develop to blastocyst stage A fraction of the cytoplasm from in vitro matured oocytes was collected and snap frozen. The oocytes were chemically activated and presumptive ...
ORGANISM(S): Bos taurus 
2013-12-27 | E-GEOD-29191 | biostudies-arrayexpress
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