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ProteomicsBiogenesis and migration of the sperm cytoplasmic droplet requires ARRDC5 and TEX38
The maturation of spermatid to fertilization competent spermatozoa is a sophisticated process required for sexual reproduction, and biogenesis of the cytoplasmic droplet (CD) is a key event. Here we demonstrate that two proteins with testis-specific expression, ARRDC5 and TEX38, physically interact,...
ORGANISM(S): Mus musculus (Mouse) 
2026-03-02 | PXD063909 | Pride
Cytoplasmic droplet Lc-ms Arrdc5-/- or tex38-/- mice Spermatid Spermatozoa 
UnknownSYPL1 defines a vesicular pathway essential for sperm cytoplasmic droplet formation and male fertility.
Not available
S-EPMC10444883 | biostudies-literature
ProteomicsProteomic characterization of cytoplasmic lipid droplets in human metastatic breast cancer cells
Untargeted LC-MS/MS analysis of the isolated cytoplasmic lipid droplet fraction of MCF10CA1a metastatic breast cancer cells
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2021-01-20 | MSV000086731 | MassIVE
GenomicsExamination of hepatic SREBP-2 binding using ChIP-Seq
Sterol regulatory element binding proteins (SREBPs) are key transcriptional regulators of lipid metabolism. To define functional differences between the three mammalian SREBPs we are using genome-wide ChIP-seq with isoform-specific antibodies and chromatin from select tissues of mice challenged with...
ORGANISM(S): Mus musculus 
2011-03-22 | E-GEOD-28082 | biostudies-arrayexpress
UnknownCounting cytoplasmic incompatibility factor mRNA using digital droplet PCR.
Not available
S-EPMC12324539 | biostudies-literature
UnknownBiogenesis and migration of the sperm cytoplasmic droplet require ARRDC5 and TEX38.
Not available
S-EPMC12927553 | biostudies-literature
ProteomicsMapping the lipid droplet proteome by using proximity labeling in ccRCC cell lines
Comprehensive understanding of the lipid droplet (LD) proteome in ccRCC cells is lacking. In this study, we employed TurboID, an engineered biotin ligase with great efficiency for enzyme-catalyzed proximity labeling, to map the spatial proteome of LDs in ccRCC cells.
ORGANISM(S): Homo sapiens (Human) 
2025-08-28 | PXD048174 | Pride
Lipid droplet Turboid Proximity labeling Clear cell renal cell carcinoma Hilpda 
UnknownApoptosis-induced mitochondrial dysfunction causes cytoplasmic lipid droplet formation.
Not available
S-EPMC3422477 | biostudies-literature
UnknownCompartmentalization of membrane trafficking, glucose transport, glycolysis, actin, tubulin and the proteasome in the cytoplasmic droplet/Hermes body of epididymal sperm.
Not available
S-EPMC4554921 | biostudies-literature
UnknownLipid droplet formation is dispensable for endoplasmic reticulum-associated degradation.
Not available
S-EPMC3151032 | biostudies-literature
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