Sort   by:  
 Page size 
Oocytes must accumulate and store maternal factors such as proteins during growth to sustain the first stages of embryonic development. How mammalian oocytes store maternal proteins is not understood. Here, we show that mouse and human oocytes store proteins on cytoplasmic lattices. With super-resol...
ORGANISM(S): Mus musculus (Mouse) 
2023-10-23 | PXD038575 | Pride
Mammalian oocytes store proteins in cytoplasmic lattices
Mammalian oocytes store proteins for embryonic development on abundant structures known as cytoplasmic lattices (CPLs); however, the mechanisms by which they achieve this are unclear, largely because the molecular composition of the lattices themselves is unknown. Here, we use cryo-electron microsco...
ORGANISM(S): Mus musculus (Mouse) 
2026-03-11 | PXD073451 | Pride
Early events of HIV-1 lifecycle, such as post-entry virus trafficking, uncoating and nuclear import, remain poorly understood due to limited information about virus-host interactions. We used a multidisciplinary approach. First, a mass spectrometry (MS)-based proteomics methodology enabled us to ide...
ORGANISM(S): Homo sapiens (Human) 
2021-01-04 | PXD020970 | Pride
Dissecting PADI6 function defines oocyte cytoplasmic lattices as regulatory hubs for fundamental cellular processes
Mammalian oogenesis is a complex mechanism entailing the maturation of primordial follicles into preovulatory follicles followed by the release of antral oocytes. In the ovary, the antral compartment consists of two populations of oocytes whose main difference regards the ability to resume meiosis a...
ORGANISM(S): Mus musculus 
To investigate the transcriptomic profile of Padi6 -/- and Tle6 -/- oocytes
ORGANISM(S): Mus musculus 
2023-11-02 | GSE222809 | GEO
Sort   by:  
 Page size