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Tick-borne encephalitis virus is an enveloped, pathogenic, RNA virus in the family Flaviviridae, genus Flavivirus. Viral particles are formed when the nucleocapsid, consisting of an RNA genome and multiple copies of the capsid protein, buds through the endoplasmic reticulum membrane and acquires ...

2023-01-06 | MTBLS6076 | MetaboLights
Early events of HIV-1 lifecycle, such as post-entry virus trafficking, uncoating and nuclear import, remain poorly understood due to limited information about virus-host interactions. We used a multidisciplinary approach. First, a mass spectrometry (MS)-based proteomics methodology enabled us to ide...
ORGANISM(S): Homo sapiens (Human) 
2021-01-04 | PXD020970 | Pride
The hepatitis E virus (HEV), a non enveloped RNA virus, causes viral hepatitis. The viral open reading frame 2 (ORF2) protein represents the capsid protein of HEV which is known to cause endoplasmic reticulum stress in ORF2 expressing cells. The initiation of endoplasmic reticulum stress induced apo...
ORGANISM(S): Homo sapiens 
Here, we present our investigation of the viral proteins of the capsid of adeno-associated viruses via top-down mass spectrometry on the LC timescale. Characterization was improved through the use of proton transfer charge reduction
ORGANISM(S): Human Aav 
2024-06-14 | MSV000095045 | MassIVE
Analysis of VEEV Capsid Interaction Sites
This project encompasses co-IP mass spectrometry results using anti-dArc or isotype antibodies to pulldown dArc capsid binding partners from whole cell lysate of C2C12 cells
ORGANISM(S): Mus musculus (Mouse) Drosophila melanogaster (Fruit fly) 
2026-08-19 | PXD075863 | Pride
Due to the limited size of viral genomes, most viral proteins are multifunctional; yet most direct-acting antivirals are designed as single-function inhibitors. The dengue virus (DENV) capsid protein serves as a building block for new virions while also interacting with multiple host factors to remo...
ORGANISM(S): Homo sapiens (Human) 
2026-03-30 | PXD063557 | Pride
YFV Capsid changes to mRNA transcriptome of Huh7 cells
Chromatin accessibility analysis of Huh7 cells upon YFV capsid expression
The emergence of mosquito-borne diseases because of climate change emphasizes the need to study arbovirus-vector protein-protein interactions (PPI) to better understand viral replication and transmission. One such human pathogenic arbovirus is Zika virus (ZIKV; Flaviviridae), transmitted by Aedes ae...
ORGANISM(S): Aedes aegypti 
2021-03-21 | PXD020565 | Pride
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