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This article contains mass spectrometry (MS) data investigating small molecule changes as an effect of a triple peroxisome proliferator-activated receptor (PPAR-pan) agonist GW625019 in the liver as described in the manuscript “PPAR-pan Activation Induces Hepatic Oxidative Stress and Lipidomic Re...

2016-05-13 | MTBLS303 | MetaboLights
To address the question of how photosynthetic bacterium Rhodopseudomonas palustris metabolize lignin derived compound p-coumarate, transcriptomics and quantitative proteomics were combined to characterize gene expression profiles at both the mRNA level and protein level in Rhodopseudomonas palustris...
ORGANISM(S): Rhodopseudomonas palustris 
We used the compond 7 developped by Jianwei Chen's group in P. aeruginosa under different concentrations (blank, 8*MIC and 16*MIC). Then we conducted the differential proteomics testing.
ORGANISM(S): Pseudomonas aeruginosa PAO1 
2026-01-17 | PXD069942 | Pride
GenX (HFPO-DA) is a per- and polyfluoroalkyl substance (PFAS) increasingly used as a replacement for legacy compounds such as PFOA, but its environmental persistence and potential toxicity raise concerns. Traditional chemical risk assessment is time- and resource-intensive and provides limited insig...
ORGANISM(S): Danio rerio 
Coenzyme A (CoA) is an essential molecule acting in metabolism, post-translational modification, and regulation of gene expression. While all organisms synthesize CoA, many, including humans, are unable to produce its precursor, pantothenate. Intriguingly, like most plants, fungi and bacteria, paras...
2022-03-21 | MTBLS2501 | MetaboLights
10^7 HL-60 cells were treated with 10 uM ATRA for two and five days. 10% whole cell lysates were saved as input after genomic DNA was broken into 200-500 bp by sonication. 1 μg IP grade antibodies of CTCF, H3K4me3 or H3K27me3 (CST, Boston, USA) were incubated with the rest of the lysate overnight, f...
ORGANISM(S): Homo sapiens 
In the present work, we sought to identify exhaustively the endogenous substrates ubiquitinated and degraded by the E3 ubiquitin ligase RNF111 in presence of TGF-β signaling by performing label free quantitative proteomics after enrichment of ubiquitinated proteins (ubiquitome) in parental U2OS cell...
ORGANISM(S): Homo sapiens (Human) 
2021-11-17 | PXD025890 | Pride
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