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MetabolomicsExperimental and computational approaches for deep metabolome annotation with application to the ecotoxicological model organism Daphnia magna

Identifying metabolomes with greater coverage and confidence is a critical step towards interpreting the metabolic basis of human and environmental health. Yet for over two decades the field of metabolomics has been inhibited by limited metabolite identification. To address this, we developed the...

MTBLS2273 | MetaboLights
MetabolomicsMetabolomics reveals an involvement of pantothenate for male production responding to the short-day stimulus in the water flea, Daphnia pulex
Under favorable conditions, the micro-crustacean Daphnia pulex produces female offspring by parthenogenesis, whereas in response to various unfavorable external cues, they produce male offspring to induce sexual reproduction (environmental sex determination: ESD). We recently established a suitable ...
2017-04-03 | MTBLS259 | MetaboLights
MetabolomicsInvestigating the Mechanisms of Silver Nanoparticle Toxicity in Daphnia magna: A Multi-Omics Approach
Silver nanoparticles (AgNPs), one of the most common nanomaterials in use today, have been shown to enter the aquatic environment from use of commercially obtained products. Although acute toxicity has been shown in vitro and in vivo, there is still a great deal of uncertainty surrounding the molecu...
2017-05-08 | MTBLS260 | MetaboLights
TranscriptomicsThe Ecoresponsive Genome of Daphnia pulex: Empirical annotation of the Daphnia pulex genome
This SuperSeries is composed of the following subset Series: GSE25841: Evolutionary Diversification of Duplicated Genes; Experiment A GSE25843: Evolutionary Diversification of Duplicated Genes; Experiments B-I, M-P GSE25845: Evolutionary Diversification of Duplicated Genes; Experiments B-I GSE25850:...
ORGANISM(S): Daphnia pulex 
2011-02-01 | E-GEOD-25823 | biostudies-arrayexpress
MetabolomicsUntargeted metabolomics of Daphnia magna exposed to a lithium cobalt oxide nanomaterial
Not available
ORGANISM(S): Daphnia magna 
ST001807 | MetabolomicsWorkbench
ProteomicsDaphnia pulex_Lysine acetylation
Daphnia (Daphnia pulex) is a small planktonic crustacean and a key constituent of aquatic ecosystems. It is commonly used as a model organism for studying environmental toxic challenges. In the past decade, a Daphnia genomic information and proteomic dataset has been developed. This dataset has expa...
ORGANISM(S): Daphnia pulex (Water flea) 
2016-01-05 | PXD002441 | Pride
D. pulex  lysine acetylation  post-translational modification  proteomics 
ProteomicsThe influence of simulated microgravity on the proteome of Daphnia magna
Background/Objectives: The waterflea Daphnia is an interesting candidate for biore- generative life support systems (BLSS). These animals are particularly promising be- cause of their central role in the limnic food web and its mode of reproduction. How- ever, the response of Daphnia to altered grav...
ORGANISM(S): Daphnia magna 
2015-09-08 | PXD002096 | Pride
Functional weightlessness Bioregenerative life support system Daphnia Clinorotation Proteomics 
ProteomicsImproving the proteome coverage of Daphnia magna
To improve proteome coverage in Daphnia, we established an easy-to-use procedure based on the LC-MS/MS of whole daphnids and dissected daphnia guts separately. Using a comprehensive spectral library, generated by gas-phase fractionation (GPF) and a data-independent acquisition method, we identified ...
ORGANISM(S): Daphnia magna Sus scrofa domesticus (domestic pig) 
2022-11-17 | PXD029198 | Pride
Dia Mass spectrometry Gut Aquatic pollution Ecotoxicoproteomics Daphnia 
ProteomicsShotgun ecotoxicoproteomics of Daphnia pulex: biochemical effects of the anticancer drug tamoxifen
Among pollutants released into the environment by human activities, residues of pharmaceutical agents have been identified worldwide, and are an increasing matter of concern because of their potential impact on ecosystems. Because micro-crustaceans, such as daphnids, are sensitive to chemicals and a...
ORGANISM(S): Daphnia pulex (Water flea) 
2014-10-31 | PXD001257 | Pride
Tamoxifen Daphnia pulex Ecotoxiproteomics Lc-ms/ms 
TranscriptomicsEffects of microcystis on Daphnia pulex
Although cyanobacteria produce a wide range of natural toxins that impact aquatic organisms, food webs and water quality, the mechanisms of toxicity are still insufficiently understood. Here, we implemented a whole-genome expression microarray to identify pathways, gene networks and paralogous gene ...
ORGANISM(S): Daphnia pulex 
2012-07-26 | E-GEOD-36635 | biostudies-arrayexpress
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