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ProteomicsShotgun ecotoxicoproteomics of Daphnia pulex: biochemical effects of the anticancer drug tamoxifen
Among pollutants released into the environment by human activities, residues of pharmaceutical agents have been identified worldwide, and are an increasing matter of concern because of their potential impact on ecosystems. Because micro-crustaceans, such as daphnids, are sensitive to chemicals and a...
ORGANISM(S): Daphnia pulex (Water flea) 
2014-10-31 | PXD001257 | Pride
Tamoxifen Daphnia pulex Ecotoxiproteomics Lc-ms/ms 
ProteomicsImproving the proteome coverage of Daphnia magna
To improve proteome coverage in Daphnia, we established an easy-to-use procedure based on the LC-MS/MS of whole daphnids and dissected daphnia guts separately. Using a comprehensive spectral library, generated by gas-phase fractionation (GPF) and a data-independent acquisition method, we identified ...
ORGANISM(S): Daphnia magna Sus scrofa domesticus (domestic pig) 
2022-11-17 | PXD029198 | Pride
Dia Mass spectrometry Gut Aquatic pollution Ecotoxicoproteomics Daphnia 
ProteomicsProteome Integral Solubility Alteration assay in zebrafish embryo for exploring exposure to bioactive compounds including pollutants and chemicals mixtures
The One Health initiative connects human and animal health with their shared environment. The development of novel methodology to unbiased identification of mechanisms of action of chemicals and chemicals mixtures would address one of today´s challenges of environmental and human toxicology. Zebrafi...
ORGANISM(S): Danio rerio (Zebrafish) (Brachydanio rerio) 
2022-02-28 | PXD021670 | Pride
Thermal proteome profiling Bioactive compound Pollutants Drug target Zebrafish embryo Biodiscovery Novel drug Proteome integral solubility alteration assay Chemical mixtures 
ProteomicsProteomics of Gammarus fossarum A individuals sampled from the wild
Next-generation proteomics of Gammarus fossarum A animals sampled from the Seebach river in north-eastern France.
ORGANISM(S): Gammarus fossarum 
2020-04-17 | PXD014166 | Pride
Shotgun proteomics Population Sentinel Ecotoxicoproteomics Gammarids 
ProteomicsProteomics of Gammarus pulex individual males sampled from the wild
Next-generation proteomics of Gammarus pulex males for characterizing the potential proteome divergence induced in one site by natural bioavailable mono-metallic contamination (cadmium) compared to a non-contaminated site.
ORGANISM(S): Gammarus pulex 
2019-07-30 | PXD013656 | Pride
Variability Cadmium Shotgun proteomics Population Toxic stress Sentinel Ecotoxicoproteomics Gammarids 
ProteomicsProteomics of Gammarus pulex individual females sampled from the wild
Next-generation proteomics of Gammarus pulex females for characterizing the potential proteome divergence induced in one site by natural bioavailable mono-metallic contamination (cadmium) compared to a non-contaminated site.
ORGANISM(S): Gammarus pulex 
2019-07-30 | PXD013712 | Pride
Variability Cadmium Shotgun proteomics Population Toxic stress Sentinel Ecotoxicoproteomics Gammarids 
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