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UnknownFollicular lymphoma cells induce changes in T-cell gene expression and function: potential impact on survival and risk of transformation.
Not available
S-EPMC3709054 | biostudies-literature
MetabolomicsBrown and beige adipose tissue regulate systemic metabolism through a metabolite interorgan signaling axis
Brown and beige adipose tissue are emerging as distinct endocrine organs. These tissues are functionally associated with skeletal muscle, adipose tissue metabolism and systemic energy expenditure, suggesting an interorgan signaling network. Using metabolomics, we identify 3-methyl-2-oxovaleric acid,...
2022-03-03 | MTBLS2436 | MetaboLights
Genomicsba3dbe29-0fd7-4ee5-99b8-d69d3c381e6e - samples
The BAM files for WES and RNA seq used in the article "Molecular Profiling Reveals Unique Immune and Metabolic Features of Melanoma Brain Metastases." on cancer Discovery 2019. PMID: 30787016 PMCID: PMC6497554. Authors : Grant M Fischer, ..., Michael A Davies.
EGAD00001005046 | EGA
ProteomicsThe Bloom’s syndrome helicase BLM functions as a homodimer within the Bloom’s complex
Homologous recombination (HR) is an essential and highly regulated cellular process. Unintended HR in somatic cells is potentially deleterious; it can result in translocations and/or somatic cell loss of heterozygosity. This is suppressed by the BLM protein in combination with topoisomerase III, RM...
ORGANISM(S): Homo sapiens (Human) 
2022-01-17 | PXD011078 | Pride
Blm Crosslinking ms Structural proteomics Bloom’s syndrome 
UnknownTransformation of follicular lymphoma to diffuse large B-cell lymphoma proceeds by distinct oncogenic mechanisms.
Not available
S-EPMC2532951 | biostudies-literature
ProteomicsAncient genomic linkage of alpha-globin and Nprl3 couples metabolism with erythropoiesis
Development of red blood cells from progenitors requires profound reshaping of both gene expression and metabolism. How these processes are coupled is unclear. Nprl3, an inhibitor of mTORC1, has remained in synteny with the -globin genes for >500 million years, and harbours most of the -globin enha...
ORGANISM(S): Mus musculus (Mouse) 
2025-02-12 | PXD060557 | Pride
Red blood cells Nprl3 Erythropoiesis 
GenomicsMolecular Profiling Reveals Unique Immune and Metabolic Features of Melanoma Brain Metastases
There is a critical need to improve our understanding of the pathogenesis of -melanoma brain metastases (MBM). Thus, we performed RNA sequencing on 88 resected MBMs and 42 patient-matched extracranial metastases; tumors with sufficient tissue also underwent whole-exome sequencing, T-cell receptor se...
EGAS00001003672 | EGA
GenomicsImmune and Metabolic Features of Brain Metastases Melanoma (Cancer Discovery) Data Access Committee
Data Access Committee EGAC00001001216
EGAC00001001216 | EGA
UnknownTwo Randomized Trials of Neutralizing Antibodies to Prevent HIV-1 Acquisition.
Not available
S-EPMC8189692 | biostudies-literature
UnknownEffect of Lower Tidal Volume Ventilation Facilitated by Extracorporeal Carbon Dioxide Removal vs Standard Care Ventilation on 90-Day Mortality in Patients With Acute Hypoxemic Respiratory Failure: The REST Randomized Clinical Trial.
Not available
S-EPMC8408762 | biostudies-literature
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