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TranscriptomicsTranscription profiling of mouse skin carcinogenesis in FVB/N and Tg.Ac mice
Female FVB/N and Tg.Ac (hemizygotes) mice 3-5 weeks of age were purchased from Harlan UK and Taconic UK, respectively. The mice were contained in an isolator and maintained at 19C with 50% relative humidity and a 12-hour light-dark cycle. Following a 1 week acclimatisation period the dorsal skin o...
ORGANISM(S): Mus musculus 
2005-10-01 | E-MEXP-188 | biostudies-arrayexpress
TranscriptomicsTemporal transcriptomics suggest that twin-peaking genes reset the clock
The mammalian suprachiasmatic nucleus (SCN) drives daily rhythmic behavior and physiology, yet a detailed understanding of its coordinated transcriptional programmes is lacking. To reveal the true nature of circadian variation in the mammalian SCN transcriptome we combined laser-capture microdissect...
ORGANISM(S): Mus musculus 
2015-11-03 | E-GEOD-72095 | biostudies-arrayexpress
UnknownRecombinant human PRG4 (rhPRG4) suppresses breast cancer cell invasion by inhibiting TGFβ-Hyaluronan-CD44 signalling pathway.
Not available
S-EPMC6667139 | biostudies-literature
TranscriptomicsTranscriptome analysis of potato tubers: Effects of different agricultural practices
The use of profiling techniques such as transcriptomics, proteomics, and metabolomics has been proposed to improve the detection of side effects of plant breeding processes. This paper describes the construction of a food safety-oriented potato cDNA microarray (FSPM). Microarray analysis was perform...
ORGANISM(S): Solanum tuberosum 
2009-02-01 | E-GEOD-11875 | biostudies-arrayexpress
UnknownComparisons with amyloid-β reveal an aspartate residue that stabilizes fibrils of the aortic amyloid peptide medin.
Not available
S-EPMC4367279 | biostudies-literature
ProteomicsEnforced dimerization between XBP1s and ATF6f enhances the protective effects of the unfolded protein response (UPR) in models of neurodegeneration
Alteration to endoplasmic reticulum (ER) proteostasis is observed on a variety of neurodegenerative diseases associated with abnormal protein aggregation. Activation of the unfolded protein response (UPR) enables an adaptive reaction to recover ER proteostasis and cell function. The UPR is initiated...
ORGANISM(S): Homo sapiens (Human) 
2022-09-13 | PXD022554 | Pride
Xbp1 Huntington`s disease Atf6 Upr Parkinson`s disease Er stress Protein aggregation 
TranscriptomicsTranscription profiling of mouse differentiating ventral otic Epithelial Cell line
The study of the gene expression during otic development is a source of important information for understanding the mechanism of inner ear development and subsequently create appropriate gene therapies both to prevent hearing loss and eventually to regenerate the damaged parts.This dataset contains ...
ORGANISM(S): Mus musculus 
2009-04-17 | E-GEOD-15585 | biostudies-arrayexpress
UnknownA qualitative study examining the health system's response to COVID-19 in Sierra Leone.
Not available
S-EPMC10836672 | biostudies-literature
UnknownTime-dependent mechanical behaviour of the aortic chronic dissection flap.
Not available
S-EPMC9070530 | biostudies-literature
UnknownEarly exercise in blunt chest wall trauma: protocol for a mixed-methods, multicentre, parallel randomised controlled trial (ELECT2 trial).
Not available
S-EPMC8991047 | biostudies-literature
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