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ProteomicsProteomics of Day 6 IL-2 or IL-15 expanded wild-type and Pim1/Pim2 double knockout CD8+ T cells.
T cell antigen-receptor (TCR) and cytokine receptor engagement trigger large changes in Serine/Threonine kinase signalling networks to drive T cell activation and differentiation. The role of only few kinase signalling pathways have been studied in detail, and in this context, Pim kinases are an int...
ORGANISM(S): Mus musculus (Mouse) 
2024-04-15 | PXD051213 | Pride
Lc-msms Mouse Pim1 Pim2 Cytotoxic t lymphocyte Pim kinase Il-2 Il-15 
TranscriptomicsSubmerged differentiation of Aspergillus niger in carbon-limited cultures approaching zero specific growth rate
This work presents an exploration of submerged differentiation of the ubiquitous saprophyte and industrially important fungus, Aspergillus niger, in response to a limited availability of a sole carbon and energy source, maltose. In aspergilli and other mold fungi, asexual reproduction through format...
ORGANISM(S): Aspergillus niger 
2010-07-07 | E-GEOD-21752 | biostudies-arrayexpress
TranscriptomicsAnalysis of Drosophila salivary glands and Kc cells with depleted levels of linker histone H1 [Affymetrix Expression]
Indicated cells were subjected to RNAi against linker histone H1, Nautilus (control), or GFP (control). RNA was isolated and subjected to Affymetrix GeneChIP Drosophila Genome 2.0 arrays RNA was compared from cells treated with RNAi against control (Nautilus in the case of salivary glands or GFP in...
ORGANISM(S): Drosophila melanogaster 
2013-04-22 | E-GEOD-44398 | biostudies-arrayexpress
TranscriptomicsExpression data from mouse lungs, exposed in-utero to second-hand smoke (SHS) and challenged with ovalbumin (OVA) as adults.
SHS exposure during pregnancy has adverse effects on offspring. We used microarrays to characterize the gene expression changes caused by in-utero SHS exposure and adult (19-23 weeks) OVA challenge in 23-week mouse lungs. Left lungs from Balb/c male and female mice were collected at 23 weeks of age ...
ORGANISM(S): Mus musculus 
2012-06-01 | E-GEOD-38409 | biostudies-arrayexpress
TranscriptomicsExpression data from mouse lungs exposed in-utero and/or as an adult to second-hand smoke (SHS)
Second-hand smoke (SHS) exposure during pregnancy has adverse effects on offspring. We used microarrays to characterize the gene expression changes caused by in-utero exposure and adult exposure to SHS in adult mouse lungs. Left lungs from Balb/c male mice were collected at 15 weeks of age for RNA e...
ORGANISM(S): Mus musculus 
2012-03-26 | E-GEOD-36810 | biostudies-arrayexpress
Transcriptomicsamit2
Like many microalgae unicellular green alga, Chlamydomonas reinhardtii also accumulates energy rich storage lipid and starch under nutrient-limited conditions, such as phosphorus (P) and nitrogen (N) limitation. To dissect the transcriptional regulation of lipid and starch biosynthesis in response t...
ORGANISM(S): Chlamydomonas reinhardtii 
2016-01-08 | E-MTAB-2556 | biostudies-arrayexpress
TranscriptomicsThe impact of experience-dependent and independent factors on gene expression in songbird brain [e12]
Songbirds provide rich natural models for studying the relationships of brain anatomy, behavioral function, environmental signals and gene expression. Under the Songbird Neurogenomics Initiative, investigators from more than a dozen laboratories collected brain samples from six species of songbird ...
ORGANISM(S): Taeniopygia guttata 
2012-05-30 | E-GEOD-36742 | biostudies-arrayexpress
UnknownAssociation of estimated sleep duration and naps with mortality and cardiovascular events: a study of 116 632 people from 21 countries.
Not available
S-EPMC6528160 | biostudies-literature
UnknownPhase 1 study of the histone deacetylase inhibitor entinostat plus clofarabine for poor-risk Philadelphia chromosome-negative (newly diagnosed older adults or adults with relapsed refractory disease) acute lymphoblastic leukemia or biphenotypic leukemia.
Not available
S-EPMC8915247 | biostudies-literature
TranscriptomicsAnalysis of Drosophila salivary glands and Kc cells with depleted levels of linker histone H1
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Drosophila melanogaster 
2013-04-22 | E-GEOD-44148 | biostudies-arrayexpress
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