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UnknownCorallopyronin A for short-course anti-wolbachial, macrofilaricidal treatment of filarial infections.
Not available
S-EPMC7746275 | biostudies-literature
ProteomicsEngineering of human myotubes towards a mature metabolic and contractile phenotype
Skeletal muscle mediates the beneficial effects of exercise, thereby improving insulin sensitivity and reducing the risk for type 2 diabetes. Current skeletal-muscle-models in vitro are incapable of fully recapitulating its physiological functions especially regarding exercise. Supplementation of IG...
ORGANISM(S): Homo sapiens (Human) 
2024-10-17 | PXD043200 | Pride
Myotubes Mass spectrometry Igf Immunohistochemistry 
ProteomicsPKC isoforms activate LRRK1 kinase by phosphorylating conserved residues (Ser1064, Ser1074 and Thr1075) within the CORB GTPase domain
Leucine-rich-repeat-kinase 1 (LRRK1) and its homologue LRRK2 are multidomain kinases possessing an atypical ROC-CORA-CORB containing GTPase domain and phosphorylate distinct Rab proteins. LRRK1 loss of function mutations cause the bone disorder osteosclerotic metaphyseal dysplasia, whereas LRRK2 mis...
ORGANISM(S): Homo sapiens (Human) 
2022-09-02 | PXD034420 | Pride
Rab7a Lrrk1 Pkc Phosphorylation 
MetabolomicsMass Spectrometry-Based Metabolic Fingerprinting Contributes to Unveil the Role of RSUME in Renal Cell Carcinoma Cell Metabolism
Clear cell renal cell carcinoma (ccRCC) is a heterogeneous disease with 50-80% patients exhibiting mutations in the von Hippel-Lindau (VHL) gene. RSUME (RWD domain (termed after three major RWD-containing proteins: RING finger-containing proteins, WD-repeat-containing proteins, and yeast DEAD (DEXD)...
2021-10-06 | MTBLS1935 | MetaboLights
ProteomicsLC-MS/MS of thoracic aorta and perivascular adipose tissue following short-term dietary methionine restriction
We are exploring pathways influenced by short-term dietary methionine restriction (MR) in thoracic aorta and associated perivascular adipose tissue (PVAT) from obese C57BL/6J male mice around 26 weeks of age. Mice were fed 60% high fat diet (HFD) until they were obese, experimental mice were given 6...
ORGANISM(S): Arachis hypogaea (Peanut) 
2025-04-07 | PXD051504 | Pride
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TranscriptomicsmiRNA profiling during cardiomyocyte-specific differentiation of murine embryonic stem cells based on two different miRNA array platforms
miRNA plays a critical role in a wide variety of biological processes Profiling miRNA expression during the differentiation of embryonic stem cells will help us to understand the regulation pathway of differentiation, therefore to explain disease mechanisms and to find possible therapeutical targets...
ORGANISM(S): Mus musculus 
2011-12-31 | E-GEOD-24066 | biostudies-arrayexpress
TranscriptomicsGenetic and Molecular Characterization of Submergence Response Identifies Subtol6 as a Major Submergence Tolerance Locus in Maize
Maize is highly sensitive to short term flooding and submergence. We aimed to discover genetic variation for submergence tolerance in maize and elucidate the genetic basis of submergence tolerance through transcriptional profiling of contrasting genotypes. A diverse set of maize nested association m...
ORGANISM(S): Zea mays 
2015-01-01 | E-GEOD-63429 | biostudies-arrayexpress
UnknownAvailability and the quality of key newborn data within routine health facility data: findings of the IMPULSE observational study in the Central African Republic, Ethiopia, Tanzania, and Uganda.
Not available
S-EPMC12677238 | biostudies-literature
TranscriptomicsDeterminants of nucleosome positioning and their influence on plant gene expression
We report the global nuclesome posiitons to study the relationship between nucleosome occupancy and gene expression in response to Coronatine in Arabidopsis We examined nucleosome occupancy and mRNA abundance in response to Coronatine in Arabidopsis rosette leaves
ORGANISM(S): Arabidopsis thaliana 
2015-05-27 | E-GEOD-64397 | biostudies-arrayexpress
UnknownTargeting lysine-specific demethylase 1 (KDM1A/LSD1) impairs colorectal cancer tumorigenesis by affecting cancer cells stemness, motility, and differentiation.
Not available
S-EPMC10310788 | biostudies-literature
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