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GenomicsAnalysis of DDX39A and DDX56 interacting proteins
Analysis of DDX39A and DDX56 interacting proteins
PRJNA633875 | ENA
ProteomicsCytosolic interaction with RNA-helicase DDX39A titrates viral RNA G-quadruplex mediated α-Synuclein amyloidogenesis
Amyloid aggregates of α-Synuclein are hallmark of Parkinson’s Disease (PD) and related neurodegenerative diseases. α-Synuclein, being an non-canonical RNA-binding protein (RBP), associates with other RBPs within cytosolic RNA-protein granules to modulate mRNA-stability. Conversely, mRNA G-quadruplex...
ORGANISM(S): Homo sapiens (Human) 
2026-09-05 | PXD075151 | Pride
Α-synuclein Rna g-quadruplex Ddx39a Viral infection Phase separation Amyloids 
ProteomicsCytosolic interaction with RNA-helicase DDX39A titrates viral RNA G-quadruplex mediated α-Synuclein amyloidogenesis
Amyloid aggregates of α-Synuclein are hallmark of Parkinson’s Disease (PD) and related neurodegenerative diseases. α-Synuclein, being an non-canonical RNA-binding protein (RBP), associates with other RBPs within cytosolic RNA-protein granules to modulate mRNA-stability. Conversely, mRNA G-quadruplex...
ORGANISM(S): Homo sapiens (Human) 
2026-09-05 | PXD075221 | Pride
Α-synuclein Rna g-quadruplex Ddx39a Viral infection Phase separation Amyloids 
GenomicsUnwinding the roles of DEAD-box RNA helicases DDX39A and DDX39B in alternative RNA splicing
Unwinding the roles of DEAD-box RNA helicases DDX39A and DDX39B in alternative RNA splicing
PRJNA1064916 | ENA
UnknownThe RNA helicase DDX39A binds a conserved structure in chikungunya virus RNA to control infection.
Not available
S-EPMC10722560 | biostudies-literature
UnknownParsing the roles of DExD-box proteins DDX39A and DDX39B in alternative RNA splicing.
Not available
S-EPMC11317157 | biostudies-literature
TranscriptomicsTranscriptome analysis on wild type and ddx39a mutant zebrafish embryos by Next Generation Sequencing
DEAD box RNA helicase DDX39A has been shown to regulate RNA metabolism; however its role in vertebrate development has not previously been examined. To determine the impact of loss of ddx39a on transcriptome during vertebrate early development, we pursued transcriptome analysis (RNA-Seq) on wild typ...
ORGANISM(S): Danio rerio 
2017-03-28 | GSE97067 | GEO
ProteomicsAnalysis of DDX39A and DDX56 interacting proteins
DDX39A and DDX56 recombinant proteins were assayed using commercial protein microarrays in order to detect potential interaction partners.
ORGANISM(S): Homo sapiens 
2024-03-11 | GSE150859 | GEO
TranscriptomicsUnwinding the roles of DEAD-box RNA helicases DDX39A and DDX39B in alternative RNA splicing
Dead-box RNA helicases are crucial in mRNA processing, specifically in RNA splicing. Our previous work has shown that DDX39B is responsible for regulating the splicing of IL7R exon 6 and several FOXP3 introns, which rely on DDX39B's helicase and ATPase activities, respectively [this is not accurate ...
ORGANISM(S): Homo sapiens 
2024-05-29 | GSE253261 | GEO
UnknownTRAIP enhances progression of tongue squamous cell carcinoma through EMT and Wnt/β-catenin signaling by interacting with DDX39A.
Not available
S-EPMC11610093 | biostudies-literature
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