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TranscriptomicsGrowth-rate dependency of de novo resveratrol production in chemostat cultures of an engineered Saccharomyces cerevisiae strain
Saccharomyces cerevisiae has become a popular host for production of non-native compounds. The metabolic pathways involved generally require a net input of energy. To maximize the ATP yield on sugar in S. cerevisiae, industrial cultivation is typically performed in aerobic, sugar-limited fed-batch r...
ORGANISM(S): Saccharomyces cerevisiae 
2015-12-22 | E-GEOD-65942 | biostudies-arrayexpress
UnknownImpact of neuromuscular block monitoring and reversal on postoperative pulmonary complications in thoracic surgery: a Bayesian analysis of the iPROVE-OLV trial.
Not available
S-EPMC12597387 | biostudies-literature
TranscriptomicsGBM-Space: Joint Transcriptome and Chromatin Accessibility Profiling of Glioblastoma (10x Genomics - Multiome)
Cancer cells display highly heterogeneous and plastic states in glioblastoma, an incurable brain tumour. However, how these malignant states arise and whether they follow defined cellular trajectories across tumours is poorly understood. Here, we generated a deep single cell and spatial multi-omic a...
ORGANISM(S): Homo sapiens 
2026-09-12 | E-MTAB-17183 | biostudies-arrayexpress
TranscriptomicsEngineering topology and kinetics of sucrose metabolism in Saccharomyces cerevisiae for improved ethanol yield
Sucrose is a major carbon source for industrial bioethanol production by Saccharomyces cerevisiae. In yeasts, two modes of sucrose metabolism occur: (i) extracellular hydrolysis by invertase, followed by uptake and metabolism of glucose and fructose, and (ii) uptake via sucrose-H+ symport followed b...
ORGANISM(S): Saccharomyces cerevisiae 
2011-09-05 | E-GEOD-30535 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of S. cerevisiae grown in acetate, ethanol and maltose limited conditions to investigate transcriptional regulation in controlling fluxes in central carbon metabolism
In contrast to batch cultivation, chemostat cultivation allows the identification of carbon source responses without interference by carbon-catabolite repression, accumulation of toxic products, and differences in specific growth rate. This study focuses on the yeast Saccharomyces cerevisiae, grown ...
ORGANISM(S): Saccharomyces cerevisiae 
2008-06-16 | E-GEOD-8895 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of S. cerevisiae to investigate formaldehyde as source of free-energy during growth on glucose
Previously, it has been demonstrated that formate can be utilized by Saccharomyces cerevisiae as additional energy source using cells grown in a glucose-limited chemostat. Here, we investigated utilization of formaldehyde as co-substrate. Since endogenous formaldehyde dehydrogenase activities were i...
ORGANISM(S): Saccharomyces cerevisiae 
2008-10-18 | E-GEOD-8902 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of S. cerevisiae after prolonged selection in aerobic, glucose-limited chemostat cultures
Prolonged cultivation of Saccharomyces cerevisiae in aerobic, glucose-limited chemostat cultures (dilution rate, 0·10 h–1) resulted in a progressive decrease of the residual glucose concentration (from 20 to 8 mg l–1 after 200 generations). This increase in the affinity for glucose was accompan...
ORGANISM(S): Saccharomyces cerevisiae 
2008-06-16 | E-GEOD-8898 | biostudies-arrayexpress
UnknownDopamine and serotonin neurotransmissions exert complementary control over primate approach and avoidance.
Not available
S-EPMC12804911 | biostudies-literature
TranscriptomicsYarrowia lipolytica biolipid production during D-stat setup. [Part 2]
Second part of the time-course transcriptomic profilling of the oleaginous yeast Yarrowia lipolytica, obtained during a controlled decellerostat (D-stat) setup. A nitrogen limitation was applied during the course of the D-stat to initiate and control de novo biolipid synthesis. Yarrowia lipolytica A...
ORGANISM(S): Yarrowia lipolytica 
2015-01-01 | E-GEOD-35446 | biostudies-arrayexpress
TranscriptomicsYarrowia lipolytica biolipid production during D-stat setup. [Part 1]
First part of the time-course transcriptomic profilling of the oleaginous yeast Yarrowia lipolytica, obtained during a controlled decellerostat (D-stat) setup. A nitrogen limitation was applied during the course of the D-stat to initiate and control de novo biolipid synthesis. Yarrowia lipolytica Ag...
ORGANISM(S): Yarrowia lipolytica 
2015-01-01 | E-GEOD-35445 | biostudies-arrayexpress
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