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ProteomicsToxoplasma gondii Tgj1 Hsp40 protein interaction LC-MS/MS
We identified an Hsp40 Ydj1 / Hdj2 ortholog in T. gondii, which is involved in various biological roles in T. gondii as deduced from its interactome and analysis of the ΔCXXX mutant. Among these roles are differentiation and DNA damage, as well as metabolic pathways such as translation and energy ge...
ORGANISM(S): Toxoplasma gondii 
2023-05-10 | PXD024656 | Pride
Toxoplasma Gondii hsp40 Interaction 
TranscriptomicsTranscription profiling of Drosophila male third instar larva y+ w roX1- roX2-/y vs y+ w roX1+ roX2-/y reveals roX RNAs are required for increased expression of X-linked genes in Drosophila melanogaster males
Drosophila males double transcription of their single X chromosome to equalize X-linked gene expression with females, which carry two X chromosomes. Increased transcription requires the Male-Specific Lethal (MSL) complex. One of the primary functions of the MSL complex is thought to be enrichment ...
ORGANISM(S): Drosophila melanogaster 
2008-03-13 | E-GEOD-3990 | biostudies-arrayexpress
GenomicsSubtelomeric p53 Binding Prevents Accumulation of DNA Damage at Human Telomeres
Telomeres and tumor suppressor protein TP53 (p53) function in genome protection, but a direct role of p53 at telomeres has not yet been described. Here, we have identified non-canonical p53 binding sites within the human subtelomeres that suppress the accumulation of DNA damage at telomeric repeat ...
ORGANISM(S): Homo sapiens 
2016-01-07 | E-GEOD-75528 | biostudies-arrayexpress
UnknownMitochondrial phylogenomics of pygmy grasshoppers (Orthoptera, Tetrigidae, Metrodorinae): descriptions of a new genus, two new species, and new synonyms from China.
Not available
S-EPMC12070058 | biostudies-literature
UnknownAprepitant attenuates NLRC4-dependent neuronal pyroptosis via NK1R/PKCδ pathway in a mouse model of intracerebral hemorrhage.
Not available
S-EPMC9351153 | biostudies-literature
ProteomicsA Natural Biological Adhesive from Snail Mucus for Wound Repair
The information of main proteins from the two d-SMGs were identified
ORGANISM(S): Stylommatophora environmental sample 
2022-12-12 | PXD036781 | Pride
Snail mucus，achatina fulica，helix lucorum，protein Biological adhesive 
UnknownCorrection for Deng et al., "HMGN1 Modulates Nucleosome Occupancy and DNase I Hypersensitivity at the CpG Island Promoters of Embryonic Stem Cells".
Not available
S-EPMC5974426 | biostudies-literature
ProteomicsChicken liver TMT-based proteomics
In order to investigate the chicken SLCO1B3 gene functin on the liver metabolism, we used the Yimeng blue eggshell and brown eggshell chickens as the chicken liver SLCO1B3 gene knock-down animal to do the proteomic analysis.
ORGANISM(S): Gallus gallus (Chicken) 
2021-09-09 | PXD022768 | Pride
Chicken Liver Proteome 
ProteomicsQuantitative proteome analysis reveals changes of membrane proteins in Sedum plumbizincicola under cadmium stress
Sedum plumbizincicola is an herbaceous species tolerant of excessive cadmium accumulation in above-ground tissues. The implications of membrane proteins, especially integrative membrane proteins such as transporters, in Cd detoxification in plants have received attention in recent years, but a compr...
ORGANISM(S): Sedum plumbizincicola 
2021-12-30 | PXD025302 | Pride
Cadmium stress Tmt labeling Membrane proteome Sedum plumbizincicola 
UnknownDexrazoxane may prevent doxorubicin-induced DNA damage via depleting both topoisomerase II isoforms.
Not available
S-EPMC4242484 | biostudies-literature
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