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ProteomicsThe role of DENND10 in neuronal development
Neuron development requires an elaborate network of endosomal transport pathways, defects in which underlie multiple neurological diseases. DENND10/FAM45A is an ancient protein that is important for endosomal homeostasis. However, the role of DENND10 in the nervous system remained unknown. Here, we ...
ORGANISM(S): Mus musculus (Mouse) 
2025-03-06 | PXD038623 | Pride
Neuron Neurite outgrowth Dennd10 Cad 
ProteomicsThe role of endosomal protein DENND10/FAM45A in extracellular vesicle release and cancer cell migration
Cell migration is key to tumor metastasis, the most challenging clinical problem in cancer treatment. Here we are investigating the role of DENND10/FAM45A, a recently described endosomal protein, in cancer cell migration via modulating the release of extracellular vesicles (EVs). Bioinformatics data...
ORGANISM(S): Mus musculus (Mouse) 
2024-06-14 | PXD038264 | Pride
Extracellular vesicle Mouse Dennd10 Mammary cancer 4t1 
UnknownEndosomal protein DENND10/FAM45A integrates extracellular vesicle release with cancer cell migration
Not available
S-EPMC11234546 | biostudies-literature
UnknownStructure and interactions of the endogenous human Commander complex.
Not available
S-EPMC11189303 | biostudies-literature
UnknownCommander Complex-A Multifaceted Operator in Intracellular Signaling and Cargo.
Not available
S-EPMC8700231 | biostudies-literature
UnknownStructure of the endosomal Commander complex linked to Ritscher-Schinzel syndrome.
Not available
S-EPMC10187114 | biostudies-literature
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