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UnknownDeuterosome-mediated centriole biogenesis.
Not available
S-EPMC3816757 | biostudies-literature
UnknownBiophysical and biochemical properties of Deup1 self-assemblies: a potential driver for deuterosome formation during multiciliogenesis.
Not available
S-EPMC7938805 | biostudies-literature
UnknownCDC20B is required for deuterosome-mediated centriole production in multiciliated cells.
Not available
S-EPMC6220262 | biostudies-literature
UnknownParental centrioles are dispensable for deuterosome formation and function during basal body amplification.
Not available
S-EPMC6446193 | biostudies-literature
ProteomicsIdentification of CDC20/CDC20B partners in HEK cells demonstrates that CDC20, but not CDC20B, interacts with multiple APC/C components
Multiciliated cells (MCCs) harbour dozens to hundreds of motile cilia, which beat in a synchronized and directional manner, thus generating hydrodynamic forces important in animal physiology. In vertebrates, MCC differentiation critically depends on the synthesis and release of numerous centrioles b...
ORGANISM(S): Homo sapiens (Human) 
2019-04-03 | PXD010629 | Pride
Motile cilia Deuterosome Centriole Plk1 Cdc20b Separase Cdc20 Cell cycle Hek cells 
TranscriptomicsMiR-34b regulates multiciliogenesis during organ formation in zebrafish
Multiciliated cells possess multiple motile cilia on the cell surface and are widely distributed throughout the vertebrate body to perform important physiological functions by regulating fluid movement in the intercellular space. However the molecular mechanisms underlying multiciliogenesis are not ...
ORGANISM(S): Danio rerio 
2013-06-14 | E-MEXP-3893 | biostudies-arrayexpress
TranscriptomicsAnalysis of initial step of multiciliogenesis during the differentiation of adult airway progenitors
Multiciliated cells are crucial for fluid and ion transport in epithelia of a variety of organs and their impaired development and function are seen in human diseases affecting the brain, respiratory, and reproductive tracts. Multiciliogenesis requires activation of a specialized transcription progr...
ORGANISM(S): Mus musculus 
2017-08-30 | GSE73331 | GEO
UnknownA role for Cep70 in centriole amplification in multiciliated cells.
Not available
S-EPMC7856201 | biostudies-literature
UnknownDynamics of centriole amplification in centrosome-depleted brain multiciliated progenitors.
Not available
S-EPMC6736942 | biostudies-literature
UnknownRegulation of cilia abundance in multiciliated cells.
Not available
S-EPMC6504233 | biostudies-literature
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