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Gene duplication enables the emergence of new functions by lowering the general evolutionary pressure. Previous studies have highlighted the role of specific paralog genes during cell differentiation, e.g., in chromatin remodeling complexes. It remains unexplored whether similar mechanisms extend to...
ORGANISM(S): Danio rerio (Zebrafish) (Brachydanio rerio) 
2022-03-07 | PXD027191 | Pride
Gene duplication enables the emergence of new functions by lowering the general evolutionary pressure. Previous studies have highlighted the role of specific paralog genes during cell differentiation, e.g., in chromatin remodeling complexes. It remains unexplored whether similar mechanisms extend to...
ORGANISM(S): Mus musculus (Mouse) 
2022-03-07 | PXD027387 | Pride
A progressive loss of protein homeostasis is characteristic of aging and a driver of neurodegeneration. To investigate this process quantitatively, we characterized proteome dynamics during brain aging in the short-lived vertebrate Nothobranchius furzeri combining transcriptomics and proteomics. We ...
ORGANISM(S): Mus musculus (Mouse) Nothobranchius furzeri 
2020-08-17 | PXD018399 | Pride
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