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Proteomicsp38γ and p38δ modulate innate immune response by regulating MEF2D activation
Evidence implicating p38γ and p38δ (p38γ/p38δ) in inflammation are mainly based on experiments using p38γ/p38δ deficient (p38γ/δ-/-) mice, which show low levels of TPL2, the kinase upstream of MKK1-ERK1/2 in myeloid cells. This could obscure p38γ/p38δ roles, since TPL2 is essential for regulating in...
ORGANISM(S): Mus musculus (Mouse) 
2023-08-10 | PXD042626 | Pride
Inflammation Mef2d P38δ Phosphorylation P38γ 
Proteomics- Pharmacological inhibition of deoxyhypusine synthase with GC7 in three PCa cell lines (LNCaP and DU145)
Protein synthesis plays a central role in cancer development and progression. eIF5A (eukaryotic initiation factor 5A), a translation factor activated by hypusination, is implicated in tumorigenesis, however, its mode of action is still unclear. Hypusinated eIF5A (eIF5Ahyp) promotes metastasis and tu...
ORGANISM(S): Homo sapiens (Human) 
2026-01-30 | PXD058627 | Pride
Hypusination Prostate cancer Quantitative proteomics Eif5a 
UnknownDevelopments and applications of the OPTIMADE API for materials discovery, design, and data exchange.
Not available
S-EPMC11305395 | biostudies-literature
UnknownEmulating a trial of joint dynamic strategies: An application to monitoring and treatment of HIV-positive individuals.
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S-EPMC6499640 | biostudies-literature
UnknownWhen to Monitor CD4 Cell Count and HIV RNA to Reduce Mortality and AIDS-Defining Illness in Virologically Suppressed HIV-Positive Persons on Antiretroviral Therapy in High-Income Countries: A Prospective Observational Study.
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S-EPMC4866894 | biostudies-literature
UnknownComparison of dynamic monitoring strategies based on CD4 cell counts in virally suppressed, HIV-positive individuals on combination antiretroviral therapy in high-income countries: a prospective, observational study.
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S-EPMC5492888 | biostudies-literature
UnknownThe Origin, Epidemiology, and Phylodynamics of Human Immunodeficiency Virus Type 1 CRF47_BF.
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S-EPMC9172993 | biostudies-literature
UnknownCARB-ES-19 Multicenter Study of Carbapenemase-Producing Klebsiella pneumoniae and Escherichia coli From All Spanish Provinces Reveals Interregional Spread of High-Risk Clones Such as ST307/OXA-48 and ST512/KPC-3.
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S-EPMC9279682 | biostudies-literature
UnknownPredictive factors of six-week mortality in critically ill patients with SARS-CoV-2: A multicenter prospective study.
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S-EPMC9020190 | biostudies-literature
UnknownLong-term follow-up of IPEX syndrome patients after different therapeutic strategies: An international multicenter retrospective study.
Not available
S-EPMC6050203 | biostudies-literature
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