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UnknownEfficacy and safety of Ding-Kun-Dan for female infertility patients with predicted poor ovarian response undergoing in vitro fertilization/intracytoplasmic sperm injection: study protocol for a randomized controlled trial.
Not available
S-EPMC5819272 | biostudies-literature
UnknownKun-Qi birth cohort (KQBC) study for the incidence, aetiology and risk factors of chronic kidney disease in Chinese children: a cohort profile.
Not available
S-EPMC12359510 | biostudies-literature
ProteomicsIdentification and Tetramer Structure of SPD_0310 Hemin-storage Protein Linked to Streptococcus pneumoniae Iron Homeostasis and Virulence
We found that the homologous proteins of SPD_0310 of Streptococcus pneumoniae widely exists in Gram-positive bacteria. SPD_0310 has heme binding ability. In the GST pull-down experiment, we found that it can interact with several proteins.
ORGANISM(S): Streptococcus pneumoniae serotype 2 (strain D39 / NCTC 7466) 
2022-08-12 | PXD030298 | Pride
Spd_0310 Gst pull-down Streptococcus pneumoniae 
ProteomicsPlasma proteomic profiling discovers molecular features associated with upper urinary tract urothelial carcinoma
Upper tract urothelial carcinoma (UTUC) is often diagnosed late and exhibits poor prognosis. Only limited data are available concerning potential noninvasive biomarkers for disease monitoring. Here, we investigated the proteomic profile of plasma in 362 UTUC patients and 239 healthy control samples....
ORGANISM(S): Homo Sapiens 
2023-07-12 | PXD043774 |
ProteomicsIntegrated Landscape of Plasma Metabolism and Proteome for Post-traumatic Deep Vein Thrombosisasma Metabolism and Proteome for Post-traumatic Deep Vein Thrombosis
Deep vein thrombosis (DVT) is a leading cause of morbidity and mortality after trauma. Here, we integrate metabolomics and proteomics in up to 680 individuals with and without DVT after trauma (pt-DVT) to reveal the metabolic alterations and their function, and provide potential biomarkers. We carri...
ORGANISM(S): Homo Sapiens 
2024-07-22 | PXD054131 |
ProteomicsLactylation modification omics analysis of six mouse heart samples was carried out via label-free 4D LC-MS/MS
Post-translational modification (PTM) refers to the chemical modification of proteins following translation, which can regulate protein activity, localization, folding, and interactions with other biomacromolecules (including proteins, nucleic acids, and lipids). Increasing evidence suggests that ma...
ORGANISM(S): Mus Musculus 
2026-03-30 | PXD076346 |
ProteomicsChemoproteomic Mapping of the Glycolytic Targetome in Cancer Cells
we report a Target Responsive Accessibility Profiling (TRAP) approach for the global and quantitative analysis of glycolytic metabolites targetome in native cancer cell milieu.
ORGANISM(S): Homo Sapiens 
2020-11-17 | PXD022568 |
ProteomicsPPDPF suppresses the development of hepatocellular carcinoma through TRIM21-mediated ubiquitination of RIPK1
Our study have shown that PPDPF promoted NF-κB activation through TRIM21-mediated K63-linked ubiquitination of RIPK1 in hepatocytes. Upon TNF-α stimulation, PPDPF enhances TRIM21/RIPK1 interaction and increases TRIM21-mediated K63-linked ubiquitination of RIPK1, which promotes NF-κB activation.To ma...
ORGANISM(S): Homo Sapiens 
2023-02-21 | PXD040301 |
ProteomicsProteomic analysis of chronic skin wounds in diabetic mice following electrical stimulation therapy delivered by a novel electrostimulation-hydrogel wound dressing
In this study, we established a type 2 diabetes model in C57BL/6 mice through high-fat diet induction and STZ injection. Based on this animal model, we simulated clinically common hard-to-heal chronic diabetic skin wounds by implanting a mixed bacterial fluid, including Methicillin-resistant Staphyl...
ORGANISM(S): Mus Musculus 
2023-08-29 | PXD044920 |
UnknownEffect of COVID-19 pandemic lockdowns on planned cancer surgery for 15 tumour types in 61 countries: an international, prospective, cohort study.
Not available
S-EPMC8492020 | biostudies-literature
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