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ProteomicsMolecular profiling of vascular beds in vivo by DISDIVO
We developed a new technique named as Differential Systemic Decellularization in vivo (DISDIVO) for the molecular profiling of vascular beds throughout the body. This method can by applied to murine models. Thus, the data provided here correspond to mice vascular beds obtained in vivo by DISDIVO.
ORGANISM(S): Mus musculus (Mouse) 
2018-12-06 | PXD008794 | Pride
Endothelial dysfunction In vivo Endothelial cells Disdivo Smooth muscle cells Glycocalyx 
ProteomicsCharacterization of proteome dynamics in individual vascular layers at the early stage of acute sepsis
In this study we developed a stable isotope labeled of mammals (SILAM) model coupled to the application of differential systemic decellularization in vivo (DISDIVO) to evaluate the molecular dynamics of whole organism vascular beds at the initial phase of acute sepsis. Three different vascular layer...
ORGANISM(S): Mus musculus (Mouse) 
2020-10-29 | PXD018274 | Pride
Lipopolysaccharide Endothelial dysfunction Disdivo. Endothelial cells Vascular beds 
ProteomicsVascular bed systematic profiling unravels endothelial and glycocalyx dysregulations in experimental high salt hypertension
Objective: Considerable evidence links dietary salt intake with the development of hypertension, left ventricular hypertrophy, and increased risk of stroke and coronary heart disease. Despite extensive epidemiological and basic science interrogation of the relationship between high salt (HS) intake ...
ORGANISM(S): Mus musculus (Mouse) 
2023-10-24 | PXD031228 | Pride
Cardiovascular disease  endothelial cell dysfunction  glycocalyx  high salt diet  hypertension  mass spectrometry  proteomics   
UnknownDifferential systemic decellularization in vivo to study molecular changes in each vasculature layer in murine models of disease.
Not available
S-EPMC10463255 | biostudies-literature
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