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ProteomicsIL-22 promotes postnatal formation of MUC17 glycocalyx barrier that protects host enterocytes
The apical aspects of absorptive epithelial cells form a highly organized brush border membrane (BBM), shaped by densely packed microvilli that are coated with a glycocalyx. Here, we present evidence showing that the glycocalyx forms an epithelial barrier that prevents exogenous molecules from gaini...
ORGANISM(S): Mus musculus (Mouse) 
2021-02-16 | PXD018592 | Pride
Innate immunity Mucin Intestine Microvilli Enterocyte Muc13 Microbiota Muc17 Glycocalyx 
ModelsGiantsosAdams2013 - Growth of glycocalyx under static conditions
Giantsos-Adams2013 - Growth of glycocalyx under static conditions This model is described in the article: Heparan Sulfate Regrowth Profiles Under Laminar Shear Flow Following Enzymatic Degradation. Giantsos-Adams KM, Koo AJ, Song...
2024-09-02 | BIOMD0000000830 | BioModels
ModelsGiantsos-Adams2013 - Growth of glycocalyx under static conditions
Giantsos-Adams2013 - Growth of glycocalyx under static conditions This model is described in the article: Heparan Sulfate Regrowth Profiles Under Laminar Shear Flow Following Enzymatic Degradation. Giantsos-Adams KM, Koo AJ, Song S, Sakai J, Sankaran J, Shin JH, Garcia-Carde...
2016-09-28 | MODEL1609100001 | BioModels
UnknownThe Effect of 4-Month Treatment with Glycocalyx Dietary Supplement on Endothelial Glycocalyx Integrity and Vascular Function in Patients with Psoriasis.
Not available
S-EPMC11313920 | biostudies-literature
GenomicsSingle-cell mapping of the glycocalyx in the adult human and mouse ocular surface
Single-cell mapping of the glycocalyx in the adult human and mouse ocular surface
PRJNA1272848 | ENA
GenomicsGlycocalyx micro- and nanodomains in cell-cell and cell-matrix adhesions revealed by sensitive click chemistry
Glycocalyx micro- and nanodomains in cell-cell and cell-matrix adhesions revealed by sensitive click chemistry
PRJNA1211525 | ENA
GenomicsDeubiquitinase USP2 accelerates endothelial glycocalyx degradation in sepsis-induced ALI by stabilizing MTCH2
Deubiquitinase USP2 accelerates endothelial glycocalyx degradation in sepsis-induced ALI by stabilizing MTCH2
PRJNA1480610 | ENA
TranscriptomicsGlycocalyx micro- and nanodomains in cell-cell and cell-matrix adhesions revealed by sensitive click chemistry
The glycocalyx consists of glycoproteins, glycolipids and extracellular polysaccharides at the cell surface which mediate viscoelastic and electrostatic barrier function. In molecular interactions the glycocalyx is thought to segregate locally to facilitate receptor-ligand binding, yet high-resoluti...
ORGANISM(S): Mus musculus 
2025-03-18 | GSE287160 | GEO
ProteomicsDisruption of endothelial glycocalyx after ischemic stroke onset: Activated scission activity of proHPSE by acrolein exposure
Infiltration of peripheral immune cells after blood-brain barrier (BBB) dysfunction causes severe inflammation after a stroke. Although the endothelial glycocalyx functions as a barrier to circulating cells, the relationship between stroke severity and glycocalyx dysfunction remains unclear. In this...
ORGANISM(S): Homo sapiens (Human) 
2020-11-16 | PXD021040 | Pride
Acrolein heparanase 
TranscriptomicsDeubiquitinase USP2 accelerates endothelial glycocalyx degradation in sepsis-induced ALI by stabilizing MTCH2
Sepsis remains a major cause of death worldwide. The lung is particularly vulnerable, and sepsis‑induced acute lung injury (ALI) carries high mortality. Endothelial glycocalyx degradation is an early event that promotes vascular leakage and inflammation, but the upstream regulators of this process a...
ORGANISM(S): Homo sapiens 
2026-06-30 | GSE336039 | GEO
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