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TranscriptomicsNegative energy balance and hepatic gene expression patterns in high yielding dairy cows during the early postpartum period [liver]
In high yielding dairy cows the liver undergoes extensive physiological and biochemical changes during the early postpartum period in an effort to re-establish metabolic homeostasis and to counteract the adverse effects of negative energy balance (NEB). These adaptations are likely to be mediated by...
ORGANISM(S): Bos taurus 
2014-04-08 | E-GEOD-56547 | biostudies-arrayexpress
TranscriptomicsAffymetrix SNP6 copy number data on ovarian cancer cell lines
Background: Ovarian carcinomas consist of at least five distinct diseases: high-grade serous, low-grade serous, clear cell, endometrioid, and mucinous. Biomarker and molecular characterization may represent a more biologically relevant basis for grouping and treating this family of tumors, rather th...
ORGANISM(S): Homo sapiens 
2013-08-01 | E-GEOD-48351 | biostudies-arrayexpress
TranscriptomicsNegative energy balance and splenic gene expression patterns in high yielding dairy cows during the early postpartum period [spleen]
Increased energy demands to support lactation, coupled with lowered feed intake capacity results in negative energy balance (NEB) and is typically characterized by extensive mobilization of body energy reserves in the early postpartum dairy cow. The catabolism of stored lipid leads to an increase i...
ORGANISM(S): Bos taurus 
2014-04-08 | E-GEOD-56589 | biostudies-arrayexpress
UnknownStructural basis for matriglycan synthesis by the LARGE1 dual glycosyltransferase.
Not available
S-EPMC9746966 | biostudies-literature
TranscriptomicsExpression data from late-luteal bovine endometrium
In both beef and dairy cattle, the majority of embryo loss occurs in the first 14-16 days following insemination. During this period, the embryo is completely dependent on its maternal uterine environment for development, growth and ultimately survival, therefore an optimum uterine environment is cr...
ORGANISM(S): Bos taurus 
2013-08-22 | E-GEOD-50091 | biostudies-arrayexpress
TranscriptomicsRNA-seq profiling of theca and granulosa tissue of dominant follicle at 3 stages of follicular development in cows and heifers.
Cellular mechanisms that contribute to low estradiol concentrations produced by the preovulatory ovarian follicle in cattle with a compromised metabolic status (such as lactatino) are largely unknown. To gain insight into the main metabolic mechanisms affecting preovulatory follicle function RNAseq ...
ORGANISM(S): Bos taurus 
2012-06-15 | E-GEOD-34317 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human prognostic samples from neuroblastoma patients for classification of neuroblastoma by integrating gene expression pattern with regional alterations in DNA copy number
The specific genes that influence neuroblastoma biology and are targeted by genomic alterations remain largely unknown. We quantified mRNA expression in a highly annotated series of 101 prospectively collected diagnostic neuroblastoma primary tumors and the expression profiles were determined using...
ORGANISM(S): Homo sapiens 
2008-06-12 | E-GEOD-3960 | biostudies-arrayexpress
TranscriptomicsNegative energy balance and hepatic gene expression patterns in high yielding dairy cows during the early postpartum period
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Bos taurus 
2014-04-08 | E-GEOD-56594 | biostudies-arrayexpress
ProteomicsA proteogenomic surfaceome study identifies DLK1 as an immunotherapeutic target in neuroblastoma
Cancer immunotherapies have produced remarkable results in B-cell malignancies; however, optimal cell surface targets for many solid cancers remain elusive. Here, we present an integrative proteomic, transcriptomic, and epigenomic analysis of tumor specimens along with normal tissues to identify bio...
ORGANISM(S): Homo sapiens (Human) 
2024-10-23 | PXD047474 | Pride
Neuroblastoma Antibody-drug conjugate Mass spectrometry Immunotherapy Cancer Dlk1 Surfaceome 
UnknownStatic and Dynamic Disorder in Formamidinium Lead Bromide Single Crystals.
Not available
S-EPMC9923750 | biostudies-literature
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