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ProteomicsIdentification/quantitation of human Cystatin C fragments
The data uploaded is related to the identification/quantitation of Cystatin C fragment 95-146 in human hemofiltrate. Also, the mass spectrometry analysis of Cystatin C digested with several proteases is included.
ORGANISM(S): Human 
2020-12-16 | MSV000086609 | MassIVE
TranscriptomicsGene expression data for worker honey bees experimentally exposed to a dual infection with Deformed wing virus and Nosema ceranae.
Bees from 3 unrelated colonies were injected with 1ul PBS extract containing 10^9 genome equivalent of Deformed wIng virus (DWV) and/or fed 10µl sucrose solution containing 10^5 fresh Nosema ceranae spores. Control bees were injected and fed with an equivalent DWV- and Nosema-free extract respectiv...
ORGANISM(S): Apis mellifera 
2017-03-08 | E-MTAB-5508 | biostudies-arrayexpress
ProteomicsEndogenous RALF peptide function is required for powdery mildew host colonization
The receptor kinase FERONIA (FER) is a susceptibility factor for biotrophic powdery mildew fungal pathogens in Arabidopsis thaliana, but the underlying molecular mechanisms remain largely unknown. FER is required for the perception of endogenous RAPID ALKALINIZATION FACTOR (RALF) peptides to control...
ORGANISM(S): Arabidopsis thaliana (Mouse-ear cress) 
2026-05-15 | PXD059737 | Pride
ProteomicsA strategy to disentangle direct and indirect effects on (de)phosphorylation by chemical modulators of the phosphatase PP1 in complex cellular contexts
Chemical activators and inhibitors are useful probes to identify substrates and downstream effects ofenzymes; however, due to the complex signaling environment within cells, it is challenging to distinguishbetween direct and indirect effects. This is particularly the case for phosphorylation, where ...
ORGANISM(S): Homo sapiens (Human) 
2024-01-12 | PXD044415 | Pride
Protein phosphatase-1  enzyme activators  enzyme inhibitors  phosphoproteomics  mode of action 
ProteomicsDevelopment of a Global Metabo-Lipid-Prote-omics Workflow to Compare Healthy Proximal and Distal Colonic Epithelium in Mice
A multimetabo-lipid-prote-omics workflow was developed to characterize the molecular interplay within proximal (PC) and distal (DC) colonic epithelium of healthy mice. This multiomics data set lays the foundation to better understand the two tissue types and can be used to study, for example, colon-...
ORGANISM(S): Mus musculus (Mouse) 
2024-09-04 | PXD046811 | Pride
Metabo-lipid-proteomics  methyl tert-butyl ether  mouse proximal and distal colons  multi-omics 
Proteomics4-deoxy-4-fluoro-GalNAz (4FGalNAz) is a metabolic chemical reporter of O-GlcNAc modifications, highlighting the notable substrate flexibility of O-GlcNAc transferase
Bioorthogonal chemistries have revolutionized many fields. For example, metabolic chemical reporters (MCRs) of glycosylation are analogs of monosaccharides that contain bioorthogonal functionality, like azides or alkynes. MCRs are metabolically incorporated into glycoproteins by living systems, and ...
ORGANISM(S): Homo sapiens (Human) 
2022-02-17 | PXD027333 | Pride
O-glcnac  tmt 
ProteomicsA strategy to disentangle direct and indirect effects on (de)phosphorylation by chemical modulators of the phosphatase PP1 in complex cellular contexts
Chemical activators and inhibitors are useful probes to identify substrates and downstream effects of enzymes; however, due to the complex signaling environment within cells, it is challenging to distinguish between direct and indirect effects. This is particularly the case for phosphorylation, wher...
ORGANISM(S): Homo Sapiens 
2025-10-01 | PXD044452 | panorama
ProteomicsImpact of modified atmospheres on growth and metabolism of meat-spoilage relevant Photobacterium spp. as predicted by comparative proteomics
Modified atmosphere packaging (MAP) is a common strategy to selectively prevent the growth of certain species of meat spoiling bacteria. While studies on the effectiveness of MAP are still scarce on a putative control over the population of photobacteria detected as meat spoilers, they could develop...
ORGANISM(S): Photobacterium phosphoreum Photobacterium carnosum 
2022-05-31 | PXD031343 | Pride
Proteomics Modified atmosphere packaging (map) Spoilage Meat Photobacterium 
ProteomicsTruncated N-glycans destabilize POMT1 and POMT2 but do not limit cellular O-mannosylation in HEK293 cells
Protein O-mannosylation is initiated by the ER-resident enzymes POMT1 and POMT2, both of which carry multiple N-glycans essential for proper folding and activity. Although congenital disorders of glycosylation type I (CDG-I) disrupt the early N-glycosylation process, their impact on POMT biogenesis ...
ORGANISM(S): Homo Sapiens 
2026-04-13 | PXD073179 | panorama
TranscriptomicsFree fatty acids and TNF-alpha in HepG2 cell culture
The regulation of complex cellular activities in palmitate treated HepG2 cells, and the ensuing cytotoxic phenotype, involves cooperative interactions between genes. While previous approaches have largely focused on identifying individual target genes, elucidating interacting genes has thus far rema...
ORGANISM(S): Homo sapiens 
2012-05-01 | E-GEOD-26885 | biostudies-arrayexpress
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