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UnknownSerum IL-35 Levels Are Associated With Activity and Progression of Sarcoidosis.
Not available
S-EPMC7248598 | biostudies-literature
MetabolomicsBacteroides uniformis degrades β-glucan to promote Lactobacillus johnsonii improving indole-3-lactic acid levels in alleviating colitis

The gut microbiota plays a crucial role in the onset and progression of inflammatory bowel disease (IBD). β-glucan (BG), a soluble dietary fiber widely present in oats, barley, fungi, yeast and some bacteria, has multiple bioactive properties such as mitigating intestinal inflammation; however, t...

2024-02-12 | MTBLS8950 | MetaboLights
ProteomicsDdx39 is essential for the differentiation and telomere homeostasis of Embryonic Stem Cells
identified Ddx39 and Erk3 interacting proteins by co-immunoprecipitation and mass spectrometric analysis from Mus embryonic stem cells samples
ORGANISM(S): Mus musculus (Mouse) 
2025-11-10 | PXD048543 | Pride
Ddx39 Erk2 Embryonic stem cells Coip 
MetabolomicsParabacteroides distasonis ameliorates insulin resistance via activation of intestinal GPR109a
Gut microbiota plays a key role in insulin resistance (IR). Here we perform a case-control study of Chinese adults (ChiCTR2200065715) and identify that Parabacteroides distasonis is inversely correlated with IR. Treatment with P. distasonis improves IR, strengthens intestinal integrity, and reduces ...
2023-11-01 | MTBLS7943 | MetaboLights
UnknownA Trial of Lopinavir-Ritonavir in Adults Hospitalized with Severe Covid-19.
Not available
S-EPMC7121492 | biostudies-literature
TranscriptomicsEffect of BMP4 and noggin on gene expression in murine R1 ES cells
To confirm that the SMAD1/5- and SMAD4-associated genes are direct transcriptional regulators in mESCs in response to BMP, we treated undifferentiated R1 ES cells with BMP4 or with the BMP4 antagonist noggin, which can inhibit BMP signaling effectively for 4 h. Undifferentiated R1 ES cells were trea...
ORGANISM(S): Mus musculus 
2010-03-07 | E-GEOD-20527 | biostudies-arrayexpress
ProteomicsLysine 2-hyroxyisobutyrylome, acetylome and succinylome in prokaryotes
identification of lysine 2-hyroxyisobutyrylome, acetylome and succinylome in prokaryotes
ORGANISM(S): Proteus Mirabilis Atcc 29906 Escherichia Coli 
PXD013377 |
ProteomicsLactylation of Hdac1 regulated by Ldh prevents the pluripotent-to-2C state conversion
Embryonic stem cells (ESCs) were labeled with heavy isotopes, 13C615N4-arginine (Arg10) and 13C614N2-lysine (Lys6), or light isotopes, 12C614N4-arginine (Arg0) and 12C614N2-lysine (Lys0), respectively, for a total of 7 passages to ensure efficient labeling (>97%). The ESCs labeled with heavy isotope...
ORGANISM(S): Mus Musculus 
PXD050051 |
TranscriptomicsBone marrow gene expression of pediatric acute lymphoblastic leukemia (ALL)
Pediatric acute lymphoblastic leukemia (ALL) contains cytogenetically distinct subtypes that respond differently to cytotoxic drugs. Subtype classification can be also achieved through gene expression profiling. However, how to apply such classifiers to a single patient and correctly diagnose the di...
ORGANISM(S): Homo sapiens 
2009-08-19 | E-GEOD-17703 | biostudies-arrayexpress
ProteomicsDNA-guided Photoactivatable Probe-based Chemical Proteomics Reveals the Reader Protein of mRNA Methylation
We report a DNA templated chemistry and photo-crosslinking based method to detect the readers of mRNA modification. By use of N6-methyladenosine (m6A), we illustrated that this method can be successfully utilized for labelling and enriching the readers of mRNA modification, as well as for the discov...
ORGANISM(S): Homo Sapiens 
PXD019480 |
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