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ProteomicsIdentification of ASC-interacting proteins
To explore the spatiotemporal regulation of ASC speck formation and inflammasome activation, we treated primary WT and Asc–/– bone marrow-derived macrophages (BMDMs) with LPS (500 ng/ml) and ATP (5 mM) to activate NLRP3 inflammasome activation and then performed ASC IP-MS to identify proteins that i...
ORGANISM(S): Mus musculus (Mouse) 
2026-06-29 | PXD054933 | Pride
Asc Mouse bmdm Lps and atp Nlrp3 inflammasome 
ProteomicsIdentification of ASC-interacting proteins
To explore the spatiotemporal regulation of ASC speck formation and inflammasome activation, we infected primary WT and Asc–/– bone marrow-derived macrophages (BMDMs) with the bacterium Francisella novicida to induce AIM2 inflammasome activation and then performed ASC IP-MS to identify proteins that...
ORGANISM(S): Mus musculus (Mouse) 
2024-05-29 | PXD052497 | Pride
Asc Francisella novicida Inflammasome Bmdm Mouse 
ProteomicsMetabolic Reprogramming in Hepatocellular Carcinoma: An Integrated Omics Study of Lipid Pathways and Their Diagnostic Potential
Metabolic Reprogramming in Hepatocellular Carcinoma: An Integrated Omics Study of Lipid Pathways and Their Diagnostic Potential
ORGANISM(S): Homo Sapiens 
2025-03-20 | PXD062049 |
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