Asc - OmicsDI

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Unknown (2884)
Transcriptomics (618)
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Organisms

Homo sapiens (271)
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Organisms

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unidentified (2)
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plant metagenome (1)
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biostudies-arrayexpress (467)
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Cell culture (20)
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Technology Type

Mass Spectrometry (49)
Shotgun proteomics (21)
Gel-based experiment (8)
Bottom-up proteomics (8)
Affinity purification coupled with mass spectrometry proteomics (7)
Mass spectrometry (6)
HDMSE (5)
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Data-dependent acquisition (4)
Mass spectrometry assay (2)
SWATH MS (2)
HiSeq X Ten (ILLUMINA) (1)
Illumina Human 1.2M Duo custom BeadChips v1 - Genome Studio, Illumina Human 660K Quad BeadChips - Illuminus, Illumina Human-Ref 8 v3.0 expression array (1)
Illumina HiSeq 2000 (1)
ESI (1)
MSE (1)
All-ion fragmentation (1)
SRM/MRM (1)
Top-down proteomics (1)

Instrument Platform

Illumina NovaSeq 6000 (7)
NextSeq 550 (6)
NextSeq 500 (5)
Illumina HiSeq 1500 (4)
Illumina HiSeq 2500 (4)
Illumina HiSeq 2000 (4)
Illumina HiSeq 4000 (4)
GenePix 4000A [Axon Instruments] (3)
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NA (2)
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GeneChip® HT HG-U133+ PM 24-Array Plate (Affymetrix); GeneTitan (Affymetrix) (1)
SensationPlus kit (Affymetrix) (1)
RNeasy Mini Kit (Qiagen); Nanodrop 1000 Spetrophotometer (Thermo Scientific); Agilent 2100 Bioanalyzer (Agilent Technologies) (1)
Not applicable (1)
Gene Titan Instrument system (1)
Affymetrix GeneChip WT Labeling Kit (1)
NanoDrop ND-1000A spectrophotometer. Agilent Bioanalyzer 2100 (1)
NextSeq 1000 (1)
MinION (1)
Agilent 7890B/5977B GC/MS with Electron Impact Ionization (EI) (1)
AmaZon ETD (1)
SYNAPT G2-Si (1)

Publication Date

2010 (94)
2013 (74)
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2012 (45)
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2015 (43)
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2011 (42)
2016 (32)
2026 (28)
2020 (27)
2019 (27)
2008 (26)
2021 (21)
2009 (20)
2018 (19)
2007 (12)
2017 (10)
2005 (5)
2006 (3)

UNIPROT ID/AC

A0A1S3MBI7 (1)
A0A1S3RDV7 (1)
A0A1S3SLA8 (1)
B5X3P0 (1)
A0A1S3N3T3 (1)
A0A1S3NZZ4 (1)
A0A1S3P094 (1)
A0A1S3PY93 (1)
Q19VI0 (1)
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A0A1S3NHN0 (1)
A0A1S3KZD6 (1)
A0A1S3SD21 (1)
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A0A1S3P3J9 (1)
A0A1S3LD76 (1)
A0A1S3LEH9 (1)
A0A1S3MF70 (1)
A0A1S3MF67 (1)
A0A1S3MEX0 (1)
A0A1S3MEU5 (1)
A0A1S3RYH9 (1)
A0A1S3RYI5 (1)
A0A1S3P4C7 (1)
A0A1S3P297 (1)
A0A1S3P8N0 (1)
A0A1S3PB08 (1)
A0A1S3N1B9 (1)
C0HBN7 (1)
A0A1S3LIF1 (1)

CHEBI ID

CHEBI:13097 (1)
CHEBI:21278 (1)
CHEBI:63163 (1)
CHEBI:6209 (1)
CHEBI:44590 (1)
CHEBI:21260 (1)
CHEBI:44513 (1)
CHEBI:6206 (1)
CHEBI:44708 (1)
CHEBI:44466 (1)
CHEBI:13094 (1)
CHEBI:47822 (1)
CHEBI:60107 (1)
CHEBI:21486 (1)
CHEBI:60111 (1)
CHEBI:43088 (1)
CHEBI:47823 (1)
CHEBI:28538 (1)
CHEBI:47819 (1)
CHEBI:47821 (1)
CHEBI:21601 (1)
CHEBI:7203 (1)
CHEBI:77859 (1)
CHEBI:19473 (1)
CHEBI:11524 (1)
CHEBI:1021 (1)
CHEBI:12542 (1)
CHEBI:47984 (1)
CHEBI:1022 (1)
CHEBI:42925 (1)

Metabolite Name

Argininosuccinic acid (3)
Urocanic acid (3)
Marmesin (2)
Glycine (2)
N-Acetylglutamine (2)
Isovanillic acid (2)
L-histidine (2)
Thiamine (2)
N6-Acetyl-L-lysine (2)
Biopterin (2)
Aspartame (2)
Kynurenic acid (2)
Ornithine (2)
Pyridoxine (2)
Dihydrothymine (2)
L-Glutamic acid (2)
Cortisone (2)
Cis-4-Hydroxy-D-proline (2)
Methionine (2)
Choline (2)
Taurine (2)
Xanthosine (2)
Docosahexaenoic acid (2)
5-Aminolevulinic acid (2)
Adenosine (2)
Guanine (2)
Sarcosine (2)
Isoleucine (2)
Deoxyinosine (2)
Deoxyguanosine (2)

First Public Date

2024 (39)
2023 (38)
2025 (32)
2020 (31)
2026 (28)
2022 (28)
2019 (28)
2014 (23)
2021 (18)
2017 (9)
2018 (8)
2016 (6)
2015 (6)
2013 (4)

Modelling Approach

Ordinary differential equation model (1)
Constraint-based model (1)

Study status

Completed (3)
Not yet recruiting (1)

Lab affiliation

MRC Toxicology Unit, University of Cambridge, UK (4)
Head of Laboratory Neuro-Oncology, Clinical and Cancer Proteomics, Neurology (2)
Key Laboratory for Experimental Teratology of the Ministry of Education, Advanced Medical Research Institute, Qilu Hospital, Cheeloo College of Medicine, Shandong University (2)
Department of Immunology, St. Jude Children's Research Hospital (1)
Department of Science and Environment, Roskilde University, Roskilde, Denmark (1)
Principal Investigator | The Ernst and Kaethe Ascher Career Development Chair | The Department of Immunology and Regenerative Biology | Weizmann-UK Building, Room 17 | Weizmann Institute of Science | Rehovot 76100, ISRAEL | Tel: +972-8-934-4937 (1)
Department of Medical and Translational Biology (MTB), Faculty of Medicine, Umeå University, 90187 Umeå, Sweden (1)
Department of Biochemistry and Tissue Biology, Institute of Biology, University of Campinas, Campinas, SP, Brazil (1)
PCF, Biozentrum, University of Basel, Swizerland (1)
Technische Universität Dresden Internationales Hochschulinstitut Zittau Juniorprofessur für Bioanorganische Chemie (1)
Department of Laboratory Medicine and Advanced Biotechnologies, Istituto Mediterraneo per i Trapianti e Terapie ad Alta Specializzazione (IRCCS - ISMETT) Via Ernesto Tricomi, 5 - 90127 Palermo (1)
Department of Health Technology and Informatics, The Hong Kong Polytechnic University, Hong Kong (1)
IRCCS Istituto Ortopedico Galeazzi, Laboratorio di Applicazioni Biotecnologiche, Milan, Italy Department of Biomedical, Surgical and DentalSciences, Università degli Studi di Milano, Milan, Italy (1)
CNRS UMS3444-Protein Science Facility (1)
Laboratory for Medical Mass spectrometry Aalborg University Fredrik Bajersvej 3B 9220 Aalborg (1)
Medizinische Proteom-Center 44801 Bochum, Germany (1)
Institute of Systems Biomedicine, School of Basic Medical Sciences, Peking University Health Science Center, Beijing, China (1)
Department of Medical Biotechnology and Laboratory Science, Chang Gung University, Taoyuan, Taiwan (1)
KTH Royal Institute of Technology, Sweden (1)
Florence and Herbert Irving Endowed Professor of Medicine Columbia University Irving Medical Center (1)
Inserm U1183 Institut de Médecine Régénératrice et Biothérapies (IRMB Equipe 1 France (1)
Inserm U1016, Institut Cochin, Cnrs UMR8104, Université Paris Descartes, Sorbonne Paris Cité, Paris, France (1)
South China Agricultural University (1)
PhD Professor of Biochemistry & Corresponding member ofSerbian Academy of Sciences and Arts University of Belgrade-Faculty of Chemistry, Center of Excellence for Molecular Food Sciences and Department of Biochemistry, Studentski trg 12-16, 11 000 Belgrade, Serbia. Professor of Food Chemistry Department of Environmental Technology, Food Technology and Molecular Biotechnology, Ghent University Global Campus, Yeonsu-Gu, 21985 Incheon, Republic of Korea (1)
Department of Immunobiology, University of Lausanne, Switzerland (1)
Department of Physiological Sciences, College of Veterinary Medicine, University of Florida (1)
Department of Bioanalytics, Leibniz-Institut für Analytische Wissenschaften ISAS e.V., Dortmund, Germany. (1)
Department of Chemistry, Chemical Biology Centre and State Key Laboratory of Synthetic Chemistry, The University of Hong Kong (1)
University of Michigan (1)
Pharmocology Asc Professor Emory University (1)

Keyword

Moviprep (1)
PEG3350 (1)
Stool Output (1)
Polyethylene glycol with ascorbic acid (1)
Simethicone (1)
Bowel preparation (1)
Laxative (1)

IsPrivate

False (2)

Classification

bacteria (1)

Study type

Transcription profiling by array (275)
RNA-seq of coding RNA (72)
Unknown experiment type (30)
ChIP-seq (17)
Comparative genomic hybridization by array (13)
Transcription profiling by RT-PCR (8)
ChIP-chip by tiling array (6)
RNA-seq of coding RNA from single cells (6)
Methylation profiling by high throughput sequencing (6)
Transcription profiling by tiling array (4)
Other (4)
Interventional (4)
ChIP-chip by array (3)
Methylation profiling by array (3)
Human - High-throughput sequencing (2)
High-throughput sequencing (2)
Genotyping by array (2)
ATAC-seq (2)
MicroRNA profiling by array (2)
RNA-seq of non coding RNA (2)
Transcription profiling by SAGE (1)
Differential (1)
Cell line - Two-color microarray (1)
Human - One-color microarray (1)
Cell line - High-throughput sequencing (1)
RNAi profiling by array (1)
RIP-seq (1)
DNA-seq (1)

Release Date

2022 (335)
2023 (329)
2021 (311)
2025 (280)
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2020 (263)
2019 (229)
2018 (200)
2016 (152)
2015 (148)
2014 (140)
2017 (132)
2013 (123)
2010 (114)
2012 (80)
2011 (72)
2026 (47)
2008 (43)
2009 (38)
2007 (19)
2006 (9)
2005 (5)
2003 (3)
2002 (2)
2001 (2)
2004 (1)
2000 (1)

Location

Romania (1)
South Korea (1)
Australia (1)
Japan (1)

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Comparison of gene expression profiles in naïve WT and Asc-null bone marrow derived dendritic cells

The adaptor protein ASC contributes to innate immunity through the assembly of caspase-1-activating inflammasome complexes. We demonstrate that ASC plays an inflammasome-independent cell-intrinsic role in adaptive immune cells. Asc-/- mice displayed defective antigen presentation by dendritic cells ...

ORGANISM(S): Mus musculus

2012-07-08 | E-GEOD-30769 | biostudies-arrayexpress

Identification of ASC-interacting proteins

To explore the spatiotemporal regulation of ASC speck formation and inflammasome activation, we infected primary WT and Asc–/– bone marrow-derived macrophages (BMDMs) with the bacterium Francisella novicida to induce AIM2 inflammasome activation and then performed ASC IP-MS to identify proteins that...

ORGANISM(S): Mus musculus (Mouse)

2024-05-29 | PXD052497 | Pride

Identification of ASC-interacting proteins

To explore the spatiotemporal regulation of ASC speck formation and inflammasome activation, we treated primary WT and Asc–/– bone marrow-derived macrophages (BMDMs) with LPS (500 ng/ml) and ATP (5 mM) to activate NLRP3 inflammasome activation and then performed ASC IP-MS to identify proteins that i...

ORGANISM(S): Mus musculus (Mouse)

2026-06-29 | PXD054933 | Pride

Asc Mouse bmdm Lps and atp Nlrp3 inflammasome

Multi-omics analysis of glucose-mediated signaling by a moonlighting Gβ protein Asc1/RACK1

Not available

ORGANISM(S): Saccharomyces cerevisiae

ST001786 | MetabolomicsWorkbench

ASC and SAA protein interaction profiling by limited proteolysis coupled to mass spectrometry

Upon activation of ASC-containing inflammasomes, intracellular molecular aggregates (ASC specks) are assembled and released from myeloid cells into the extracellular space where they enhance the aggregation of Aβ amyloid in Alzheimer’s disease. This raises the question whether ASC is involved in add...

ORGANISM(S): Homo sapiens (Human)

2025-05-07 | PXD053372 | Pride

Inflamation Saa Lip-ms Asc

Histophilus somni strain:ASc-MMNZ-VFA-069

Histophilus somni strain:ASc-MMNZ-VFA-069 Genome sequencing

PRJNA686492 | ENA

Histophilus somni strain:ASc-MMNZ-VFA-071

Histophilus somni strain:ASc-MMNZ-VFA-071 Genome sequencing

PRJNA686664 | ENA

Histophilus somni strain:ASc-MMNZ-VFA-072

Histophilus somni strain:ASc-MMNZ-VFA-072 Genome sequencing

PRJNA686665 | ENA