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ProteomicsHuman non-small cell lung cancer cell line NCI-H661 DPPA2-4 rapid immunoprecipitation mass spectrometry (RIME, LC-MSMS)
To investigate DPPA2/4 bound proteins on chromatin we performed rapid immunoprecipitation mass spectrometry (RIME) following double crosslinking of chromatin in NCI-H661 non-small cell lung cancer cells clonal cell lines (Wild Type clones c51 & c52, DPPA2 knockout clones c41 & c42, DPPA4 knockout cl...
ORGANISM(S): Homo sapiens (Human) 
2026-03-31 | PXD070627 | Pride
Rime Dppa4 Non small cell lung cancer Ncih661 Dppa2 Human 
GenomicsGenome-wide Dppa4 binding in E14 mESC, 3T3, and P19 cells
DPPA4 is a DNA-associated factor that is highly and selectively expressed in embryonic stem cells. DPPA4 expression is strikingly downregulated upon loss of pluripotency, but is reactivated in a number of cancer cell types. It has recently been identified as an oncogene and shown to promote cell pro...
ORGANISM(S): Mus musculus 
2018-08-07 | GSE95055 | GEO
UnknownIdentification of DPPA4 and DPPA2 as a novel family of pluripotency-related oncogenes.
Not available
S-EPMC3922068 | biostudies-literature
UnknownGenomic functions of developmental pluripotency associated factor 4 (Dppa4) in pluripotent stem cells and cancer.
Not available
S-EPMC6133722 | biostudies-literature
GenomicsDPPA2 and DPPA4 are dispensable for mouse zygotic genome activation and preimplantation development
DPPA2 and DPPA4 are dispensable for mouse zygotic genome activation and preimplantation development
PRJNA753101 | ENA
GenomicsDppa2 and Dppa4 directly regulate the Dux driven zygotic transcriptional program [siRNA]
Dppa2 and Dppa4 directly regulate the Dux driven zygotic transcriptional program [siRNA]
PRJNA495359 | ENA
UnknownDppa2 and Dppa4 directly regulate the Dux-driven zygotic transcriptional program.
Not available
S-EPMC6362816 | biostudies-literature
GenomicsDppa2 and Dppa4 directly regulate the Dux driven zygotic transcriptional program [CRISPR-KO]
Dppa2 and Dppa4 directly regulate the Dux driven zygotic transcriptional program [CRISPR-KO]
PRJNA495358 | ENA
UnknownERBB3-Binding Protein 1 (EBP1) Is a Novel Developmental Pluripotency-Associated-4 (DPPA4) Cofactor in Human Pluripotent Cells.
Not available
S-EPMC5918234 | biostudies-literature
TranscriptomicsDppa4 is dispensable for embryonic stem cell identity and germ cell development, but essential for embryogenesis
Dppa4 (Developmental pluripotency-associated 4) has been identified in several highprofile screens as a gene that is expressed exclusively in pluripotent cells. It encodes a nuclear protein with a SAP-like domain and appears to be associated preferentially with transcriptionally active chromatin. It...
ORGANISM(S): Mus musculus 
2009-05-01 | GSE15173 | GEO
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