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MetabolomicsSupplementation of Bacillus sp. DU-106 reduces hypercholesterolemia and ameliorates gut dysbiosis in high-fat diet rats

Gut microbiota modulation by a probiotic is a novel therapy for hypercholesterolemia mitigation. This study initially investigated the potential hypocholesterolemic effect of Bacillus sp. DU-106 in hypercholesterolemic rats and explored its potential relation with gut microbiota. Sprague-Dawley r...

2021-04-08 | MTBLS1168 | MetaboLights
ProteomicsProteomic Analysis Reveals the Major Proteins and Pathways that Mediate the Effect of 17-β-Estradiol in Cell Division and Apoptosis in Breast Cancer MCF7 Cells
Despite extensive research, the genes/proteins and biological pathways responsible for the physiological effects of estrogen remain elusive. In this study, we employed a proteomic method to determine the effect of estrogen on global protein expression in breast cancer MCF7 cells. The expression of 7...
ORGANISM(S): Homo sapiens (Human) 
2025-05-06 | PXD049343 | Pride
Estrogen Breast cancer Proteome profiling Quantitative proteomics Cell division Silac Apoptosis. 
TranscriptomicsFunctional Annotation of the Bovine Genome
The goal of the proposed project is to generate high-quality detailed transcript and chromatin status datasets from a comprehensive set of bovine tissues, developmental stages, and cells through a set of rationally selected assays. Experimental data generated by the project have been analyzed using ...
ORGANISM(S): Bos taurus 
2022-10-13 | E-MTAB-12052 | biostudies-arrayexpress
ProteomicsEffect of Ipomoeassin F on the Proteome Profile in Triple-Negative Breast Cancer Cells
Ipomoeassin F (Ipom-F) is a natural compound that exhibits a potent cytotoxic effect on triple-negative breast cancer (TNBC) cells. The mechanism underlying this selective potency remains unclear. To elucidate this mechanism, we analyzed the proteome profiles of the TNBC MDA-MB-231 cells after expos...
ORGANISM(S): Homo sapiens (Human) 
2025-09-15 | PXD060444 | Pride
Breast cancer Human Ipomoeassin f 
UnknownPalladium-catalyzed bisthiolation of terminal alkynes for the assembly of diverse (Z)-1,2-bis(arylthio)alkene derivatives.
Not available
S-EPMC9037987 | biostudies-literature
UnknownInhibition activity of a traditional Chinese herbal formula Huang-Lian-Jie-Du-Tang and its major components found in its plasma profile on neuraminidase-1.
Not available
S-EPMC5686190 | biostudies-literature
UnknownGan-du-qing attenuates PM<sub>2.5</sub>-induced Chronic Airway Inflammation via regulating the pulmonary microbiota and metabolic profiles.
Not available
S-EPMC12457115 | biostudies-literature
UnknownReal-World Study on Chai-Shi-Jie-Du Granules for the Treatment of Dengue Fever and the Possible Mechanisms Based on Network Pharmacology.
Not available
S-EPMC10482559 | biostudies-literature
UnknownResponses of Root Endophytes to Phosphorus Availability in Peach Rootstocks With Contrasting Phosphorus-Use Efficiencies.
Not available
S-EPMC8502846 | biostudies-literature
MetabolomicsMetabolic Responses of a Model Green Microalga Euglena gracilis to Different Environmental Stresses

Euglena gracilis, a green microalga known as a potential candidate for jet fuel producers and new functional food resources, is highly tolerant to antibiotics, heavy metals and other environmental stresses. Its cells contain many high-value products, including vitamins, amino acids, pigm...

2022-08-16 | MTBLS2878 | MetaboLights
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